Fluprostenol Lactone Diol

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Names

[ CAS No. ]:
53872-60-9

[ Name ]:
Fluprostenol Lactone Diol

[Synonym ]:
Travoprost Intermediate
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aS,4R,5R,6aR)-
(3aR,4R,5R,6aS)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4R,5R,6aS)-5-Hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4R,5R,6aS)-5-hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4R,5R,6aS)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
(3aS,4R,5R,6aR)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aR,4R,5R,6aS)-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
520.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H19F3O5

[ Molecular Weight ]:
372.336

[ Flash Point ]:
268.6±30.1 °C

[ Exact Mass ]:
372.118469

[ PSA ]:
75.99000

[ LogP ]:
1.05

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.583

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Precursor & DownStream

Precursor

  • (3aR,4R,5R,6aS)-4-((E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)-2oxohexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate
  • [1,1'-biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3R)-3-hydroxy-4- [3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl ester
  • [1,1'-Biphenyl]-4-carboxylic acid(3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-5-ylester
  • (3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-y l 4-biphenylcarboxylate
  • Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate
  • (-)-Corey lactone 4-phenylbenzoate alcohol

DownStream


Related Compounds

  • Latanoprost lactone diol
  • (-)-Corey lactone diol-heptyldioxolane-d15
  • (-)-Corey lactone diol
  • Corey PG-lactone diol
  • (+/-)-Corey lactone diol
  • ent-Corey PG-Lactone Diol