Ambazone
Suppliers
Names
[ CAS No. ]:
539-21-9
[ Name ]:
Ambazone
[Synonym ]:
[1,4]Benzochinon-carbamimidoylhydrazon-thiosemicarbazon
Ambazona [inn-spanish]
Benzoqu
anginon
Faringosept
ambazon
[1,4]benzoquinone-carbamimidoylhydrazone thiosemicarbazone
promassol
primal
Benzochinon-(1,4)-monoguanylhydrazon-monothiosemicarbazon
Ambazona
Inversal
Chemical & Physical Properties
[ Density]:
1.57g/cm3
[ Boiling Point ]:
461.9ºC at 760mmHg
[ Melting Point ]:
195°C (rough estimate)
[ Molecular Formula ]:
C8H11N7S
[ Molecular Weight ]:
237.28
[ Flash Point ]:
233.2ºC
[ Exact Mass ]:
237.08000
[ PSA ]:
156.76000
[ LogP ]:
1.42280
[ Index of Refraction ]:
1.761
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF5550000
- CHEMICAL NAME :
- Guanidine, ((4-oxo-2,5-cyclohexadien-1-ylidene)amino)-, thiosemicarbazone
- CAS REGISTRY NUMBER :
- 539-21-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C8-H11-N7-S
- MOLECULAR WEIGHT :
- 237.32
- WISWESSER LINE NOTATION :
- SUYZMNU- AL6Y DYJ DUNMYZUM
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 315 mg/kg/5D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 840 mg/kg/28D-I
- TOXIC EFFECTS :
- Gastrointestinal - other changes Endocrine - changes in thymus weight Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 625 mg/kg/5D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 10 gm/L
- REFERENCE :
- STBIBN Studia Biophysica. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.1- 1966- Volume(issue)/page/year: 117,99,1987
Safety Information
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%