7-Chloroindole

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Names

[ CAS No. ]:
53924-05-3

[ Name ]:
7-Chloroindole

[Synonym ]:
7-Chloroindole
MFCD07368214
1H-Indole, 7-chloro-
7-Chloro-1H-indole
EINECS 258-865-7

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
293.0±13.0 °C at 760 mmHg

[ Melting Point ]:
55-58 °C(lit.)

[ Molecular Formula ]:
C8H6ClN

[ Molecular Weight ]:
151.593

[ Flash Point ]:
158.9±5.4 °C

[ Exact Mass ]:
151.018875

[ PSA ]:
15.79000

[ LogP ]:
3.25

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.688

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29339990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-chloroindoline
  • Triethanolamine
  • 2-Chloroaniline
  • Vinylmagnesium bromide
  • 2-Nitrochlorobenzene
  • Indole-7-boronic acid pinacol ester
  • 3-Chloro-2-nitrotoluene
  • N,N-Dimethylformamide dimethyl acetal
  • 1-(7-iodo-2,3-dihydroindol-1-yl)ethanone
  • N-(2-chlorophenyl)ethenesulfinamide

DownStream

  • 1H-Indole-3-aceticacid,7-chloro-(9CI)
  • 6-Chloro-1H-indole-3-carboxylic acid
  • 7-Nitro-1H-indole
  • TERT-BUTYL 7-CHLORO-1H-INDOLE-1-CARBOXYLATE
  • 7-Chlorotryptophan
  • 7-Chloro-1H-indole-3-carbaldehyde
  • 2-(7-chloro-1H-indol-3-yl)acetonitrile
  • 7-chloroindoline
  • 3-Bromo-7-chloro-1H-indole
  • 7-chloro-1-(cyclohexylmethyl)indole-3-carboxamide

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Structure-activity relationship study of novel necroptosis inhibitors.

Bioorg. Med. Chem. Lett. 15 , 5039, (2005)

Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. It can be induced in a FADD-deficient variant of human Jurkat T cells tr...

Synthesis of rebeccamycin and 11-dechlororebeccamycin. Faul MM, et al.

J. Org. Chem. 64(7) , 2465-2470, (1999)

The chemistry of indoles. XXXIX. A facile synthetic method for 7-substituted indoles. Somei M, et al.

Chem. Pharm. Bull. 35(8) , 3146-3154, (1987)


More Articles

Related Compounds

  • 1-BOC 7-Chloroindole
  • 5-Bromo-7-chloroindole
  • 4-bromo-7-chloroindole
  • 3-Cyano-7-chloroindole
  • 3-Bromo-7-chloroindole
  • 1-methyl-7-chloroindole