DL-Tryptophan

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Names

[ CAS No. ]:
54-12-6

[ Name ]:
DL-Tryptophan

[Synonym ]:
DL-Tryptophan
DL-Trp
3-Indol-3-ylalanine
DL-3β-Indolylalanine
H-Trp-OH
α-Aminoindole-3-propionic acid
(RS)-Tryptophan
Trp
UNII:X9U7434L7A
2-amino-3-(1H-indol-3-yl)propanoic acid
Indole-3-alanine
Propionic acid, 2-amino-3-indol-3-yl-
Alanine, 3-indol-3-yl
DL-3beta-Indolylalanine
H-DL-Trp-OH
(±)-Tryptophan
DL-a-Amino-3-indolepropionic Acid
1H-Indole-3-alanine (VAN)
Tryptophan (VAN)
(±)-2-Amino-3-(3-indolyl)propionic Acid
Indole-3-propionic acid, α-amino-
Alanine, 3-indol-3-yl-
Tryptophan
MFCD04118170
DL-Trytophane
EINECS 200-194-9
(±)-α-Amino-3-indolepropionic acid
Racemic Tryptophan
DL-Trytophan
DL-triptophan

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
447.9±35.0 °C at 760 mmHg

[ Melting Point ]:
289-290ºC

[ Molecular Formula ]:
C₁₁H₁₂N₂O₂

[ Molecular Weight ]:
204.225

[ Flash Point ]:
224.7±25.9 °C

[ Exact Mass ]:
204.089874

[ PSA ]:
79.11000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.698

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong acids.

[ Water Solubility ]:
10 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YN6129200

CHEMICAL NAME :: Tryptophan, DL-

CAS REGISTRY NUMBER :: 54-12-6

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H12-N2-O2

MOLECULAR WEIGHT :: 204.25

WISWESSER LINE NOTATION :: T56 BMJ D1YZVQ -DL

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 844 gm/kg/92W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Reproductive - Tumorigenic effects - testicular tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,1207,1979 *** REVIEWS *** TOXICOLOGY REVIEW BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,253,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3905 No. of Facilities: 559 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 6205 (estimated) No. of Female Employees: 3513 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
YN6129200

[ HS Code ]:
29339990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DL-γ-glutamaldehydic acid dimethyl acetal
Phenylhydrazine hydrochloride
methyl tryptophan
Acetyl-L-tryptophan
Indole
3-chloroalanine
diethyl 2-acetamido-2-(1H-indol-3-ylmethyl)propanedioate
rac-N-benzoyl-tryptophan methyl ester

DownStream

Indole
2'-Aminoacetophenone
1H-Pyrido[3,4-b]indole-3-carboxylicacid, 2,3,4,9-tetrahydro-1-methyl-
Necrostatin-1
4-Imidazolidinone,5-(1H-indol-3-ylmethyl)-3-phenyl-2-thioxo-
Indole-3-carboxaldehyde
Indole-3-acetaldehyde
Indole-3-pyrubate
Tryptophan, N-acetyl-, p-nitrophenyl ester, DL-
3-Methylindole

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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