4-dimethylamino-2-methylazobenzene
Suppliers
Names
[ CAS No. ]:
54-88-6
[ Name ]:
4-dimethylamino-2-methylazobenzene
[Synonym ]:
N,N,3-trimethyl-4-(phenylazo)-benzenamine
2-methyl-4-dimethylaminoazobenzene
2-MethylDAB
6-Benzolazo-3-dimethylamino-touol
N,N-Dimethyl-4-phenylazo-m-toluidine
3,N,N-Trimethyl-4-phenylazo-anilin
4-N,N-Dimethylamino-2-methylazobenzene
3,N,N-trimethyl-4-phenylazo-aniline
MFCD00008306
EINECS 200-217-2
4-Dimethylamino-2-methylazobenzene
4-Dimethylamino-2-methyl-azobenzol
m-TOLUIDINE,N,N-DIMETHYL-4-(PHENYLAZO)
2-MeDAB
Chemical & Physical Properties
[ Density]:
1.01g/cm3
[ Boiling Point ]:
150ºC / 16mmHg
[ Melting Point ]:
67-69ºC(lit.)
[ Molecular Formula ]:
C15H17N3
[ Molecular Weight ]:
239.31600
[ Flash Point ]:
190.2ºC
[ Exact Mass ]:
239.14200
[ PSA ]:
27.96000
[ LogP ]:
4.47640
[ Index of Refraction ]:
1.561
[ Water Solubility ]:
Solubility Practically insoluble in water; soluble in ethanol, acetone
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XU5950000
- CHEMICAL NAME :
- m-Toluidine, N,N-dimethyl-4-(phenylazo)-
- CAS REGISTRY NUMBER :
- 54-88-6
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 21
- MOLECULAR FORMULA :
- C15-H17-N3
- MOLECULAR WEIGHT :
- 239.35
- WISWESSER LINE NOTATION :
- 1N1&R C1 DNUNR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 345 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg/5D-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 40 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,409,1982
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H351-H413
[ Precautionary Statements ]:
P281
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R23/24;R33
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
XU5950000
[ HS Code ]:
2927000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2927000090
[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Indian J. Biochem. Biophys. 21(5) , 309-13, (1984)
Chem. Biol. Interact. 48(2) , 221-35, (1984)
In order to obtain a more precise definition of the conditions under which 2-methyl-4-dimethylaminoazobenzene (2-Me-DAB) and liver cell proliferation play a role in the initiation of hepatocarcinogene...
Eur. J. Cancer Clin. Oncol. 18(11) , 1163-70, (1982)
The hepatocarcinogen 3'-methyl-4-dimethyl-aminoazobenzene (MDAB) suppresses the accumulation of tyrosine aminotransferase in cultured foetal hepatocytes. Experiments involving liver derived from foetu...