1,2-Ethanedithiol

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Names

[ CAS No. ]:
540-63-6

[ Name ]:
1,2-Ethanedithiol

[Synonym ]:
Ethane dithiol
SH2SH
MFCD00004892
ethanedithiol
Ethylene mercaptan
Dithioglycol
ethane-1,2-dithiol
EINECS 208-752-3
1,2-Dimercaptoethane,Dithioglycol,Ethylene mercaptan
1,2-dimercaptoethane
1,2-Ethanedithiol
Dithioethyleneglycol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
144.3±13.0 °C at 760 mmHg

[ Melting Point ]:
−41 °C(lit.)

[ Molecular Formula ]:
C₂H₆S₂

[ Molecular Weight ]:
94.199

[ Flash Point ]:
44.4±0.0 °C

[ Exact Mass ]:
93.991089

[ PSA ]:
77.60000

[ LogP ]:
1.31

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
6.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.517

[ Storage condition ]:
Store at 0-5°C

[ Stability ]:
Stable. Flammable. Incompatible with oxidizing agents, bases, reducing agents, alkali metals.

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI3325000

CHEMICAL NAME :: 1,2-Ethanedithiol

CAS REGISTRY NUMBER :: 540-63-6

BEILSTEIN REFERENCE NO. :: 0505946

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C2-H6-S2

MOLECULAR WEIGHT :: 94.20

WISWESSER LINE NOTATION :: SH2SH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 342 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,249,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,235,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02101

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301-H310 + H330-H319

[ Precautionary Statements ]:
P260-P280-P284-P301 + P310-P302 + P350-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R10;R21;R23/25

[ Safety Phrases ]:
S36/37/39-S45-S26-S16-S36/37

[ RIDADR ]:
UN 3071 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
KI3325000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29309070

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-methyl-2-phenyl-1,3-dithiolane
ethyl 2-(2-methyl-1,3-dithiolan-2-yl)acetate
1,2-Dibromoethane
1,3-Dithiolane-2-thione
dichloroethane
ethene
1,2,5,6-tetrathiacyclooctane
S,S'-ethane-1,2-diyl diethanethioate
Thiirane
Ethylene glycol

DownStream

8-phenyl-1,4-dithiaspiro[4.5]decane
2-pent-1-enyl-1,3-dithiolane
2,3-Dihydro-1,4-benzodithiin
Thioanisole
2-(methylthio)ethyl disulfide
1-iodo-2-(2-methylsulfanylethylsulfanyl)benzene
4-(1,3-dithiolan-2-yl)benzonitrile
2-(1-methylpyridin-1-ium-2-yl)sulfanylethanethiol,iodide
Bis(2-mercaptoethyl) sulfide
2-[2-(2-sulfanylethylsulfanyl)ethylsulfanyl]ethanethiol

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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1,2-ethanedithiol
(1,2-ethanedithiol)2Sn(IV)
Disodium1,2-ethanedithiolate
CHOxAsH-bis(1,2-ethanedithiol)
S,S'-Bis(trimethylsilyl)-1,2-ethanedithiol
1-(2-ethylhexyl)-3,4-dihydroxypyrrolidine-2,5-dione
2-(3-Aminoazetidin-1-yl)-2-(pyridin-4-yl)acetonitrile
2-(3-Aminoazetidin-1-yl)-2-(thiophen-2-yl)acetonitrile
2-(3-Aminoazetidin-1-yl)-2-(furan-2-yl)acetonitrile
2-(3-Aminoazetidin-1-yl)-2-(5-bromofuran-2-yl)acetonitrile
2-(3-Aminoazetidin-1-yl)-2-(5-bromothiophen-2-yl)acetonitrile
2-(3-Aminoazetidin-1-yl)-2-methylpropanenitrile
2,3-Dimethyl-2-(3-(methylamino)azetidin-1-yl)butanenitrile
2-(3-Aminoazetidin-1-yl)-2-methyl-3-phenylpropanenitrile
2-(3-Aminoazetidin-1-yl)-3-phenylpropanenitrile
2-(3-(Aminomethyl)azetidin-1-yl)propanenitrile

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