4,6-dimethylpyridin-2-amine

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Names

[ CAS No. ]:
5407-87-4

[ Name ]:
4,6-dimethylpyridin-2-amine

[Synonym ]:
MFCD00006322
2-Amino-4,6-dimethylpyridine
2-Pyridinamine, 4,6-dimethyl-
4,6-Dimethylpyridin-2-Amine
6-Amino-2,4-lutidine
4,6-Dimethylpyridin-2-amin
4,6-Dimethyl-2-pyridinamine
2-Amino-4,6-dimehtylpyridine
EINECS 226-470-9

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
235.0±0.0 °C at 760 mmHg

[ Melting Point ]:
63-64 °C(lit.)

[ Molecular Formula ]:
C7H10N2

[ Molecular Weight ]:
122.168

[ Flash Point ]:
115.5±13.1 °C

[ Exact Mass ]:
122.084396

[ PSA ]:
38.91000

[ LogP ]:
1.54

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.564

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US1818000
CHEMICAL NAME :
Pyridine, 2-amino-4,6-dimethyl-
CAS REGISTRY NUMBER :
5407-87-4
BEILSTEIN REFERENCE NO. :
0002048
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H10-N2
MOLECULAR WEIGHT :
122.19
WISWESSER LINE NOTATION :
T6NJ BZ D1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 36,491,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00149

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
US1818000

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • 2,4-DIMETHYL-PYRIDINE 1-OXIDE
  • 3-(cyanomethyl)-3-methylpentanedinitrile
  • 2-Pyridinecarboxamide,4,6-dimethyl-(9CI)
  • 2,4-Lutidine
  • Methylmagnesium chloride
  • 4,6-Dimethyl-2-pyridinecarboxylic acid

DownStream

  • 2,3-Diamino-4,6-dimethylpyridine
  • 2-Brom-4,6-dimethylpyridin
  • 2-Chloro-4,6-dimethylpyridine
  • 3-nitro-6-hydroxy-2,4-dimethylpyridine
  • 5-iodo-4,6-dimethylpyridin-2-amine
  • 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE
  • 2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine
  • ethyl 2-[(4,6-dimethylpyridin-2-yl)carbamoyl]acetate
  • 4,6-Dimethylpyridin-2-ol
  • 4-Amino-N-(4,6-dimethyl-2-pyridinyl)benzamide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 5-iodo-4,6-dimethylpyridin-2-amine
  • 5-bromo-4,6-dimethylpyridin-2-amine
  • 3-bromo-4,6-dimethylpyridin-2-amine
  • 3-chloro-4,6-dimethylpyridin-2-amine
  • 5-chloro-4,6-dimethylpyridin-2-amine
  • 5-ethenyl-4,6-dimethylpyridin-2-amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 6-Bromo-3-dimethylamino-1,2,4-triazine-5(4H)-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Tert-butyl 2-amino-3-chloro-6-methylbenzoate
  • 2-Cyclopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-[3-[(3-Methylphenyl)methyl]azetidin-1-yl]prop-2-en-1-one
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide