Zorubicin
Suppliers
Names
[ CAS No. ]:
54083-22-6
[ Name ]:
Zorubicin
[Synonym ]:
Rubidazone
ZORUBICIN
Zorubicina [INN-Spanish]
zorubicine
Benzoylhydrazone daunorubicin
Zorubicin [INN]
daunomycin benzoylhydrazone
Zorubicine [INN-French]
Rubidazon
Zorubicinum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.54g/cm3
[ Molecular Formula ]:
C34H35N3O10
[ Molecular Weight ]:
645.65600
[ Exact Mass ]:
645.23200
[ PSA ]:
210.23000
[ LogP ]:
3.33700
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG3345000
- CHEMICAL NAME :
- Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha,L-lyxo-hexopyran osyl)oxy)-1,2,3,4,6,1 1- hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-na phthacenyl)ethylidene )hydrazide, (2S-cis)-
- CAS REGISTRY NUMBER :
- 54083-22-6
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C34-H35-N3-O10
- MOLECULAR WEIGHT :
- 645.72
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22500 ug/kg/5D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg/5D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42500 ug/kg/5D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rat Cells - not otherwise specified
- DOSE/DURATION :
- 2150 ug/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 38,167,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2089 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 229 (estimated) No. of Female Employees: 82 (estimated)