Isopropyl nitrite

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Names

[ CAS No. ]:
541-42-4

[ Name ]:
Isopropyl nitrite

[Synonym ]:
Isopropyl nitrite
EINECS 208-779-0
propan-2-yl nitrite
Nitrous acid, 1-methylethyl ester

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
39.0±9.0 °C at 760 mmHg

[ Melting Point ]:
134-139 °C(lit.)

[ Molecular Formula ]:
C3H7NO2

[ Molecular Weight ]:
89.093

[ Flash Point ]:
-36.8±13.2 °C

[ Exact Mass ]:
89.047676

[ PSA ]:
38.66000

[ LogP ]:
1.39

[ Vapour Pressure ]:
458.2±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.405

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RA0930000
CHEMICAL NAME :
Nitrous acid, isopropyl ester
CAS REGISTRY NUMBER :
541-42-4
BEILSTEIN REFERENCE NO. :
1698878
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C3-H7-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,79,1982
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2800 mg/m3
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(10),29,1966 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
59 mg/m3/17W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation)
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(10),29,1966 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993

Safety Information

[ Hazard Codes ]:
O,T

[ Risk Phrases ]:
8-11-23/24/25-36/37/38

[ Safety Phrases ]:
17-26-36/37/39-45

[ RIDADR ]:
1992

[ WGK Germany ]:
3

[ Packaging Group ]:
I

[ Hazard Class ]:
3.1

[ HS Code ]:
2920909090

Precursor & DownStream

Precursor

  • Isopropanol
  • 2-Iodopropane
  • 2-Bromopropane
  • Sodium 2-methylpropanoate
  • 2-λ1-oxidanylpropane
  • Propane Residual Solvent Standard
  • t-butyl nitrite
  • Nitrous acid, methylester
  • Benzophenone

DownStream

  • Diisopropyl sulfite
  • 3,5-Dichlorobenzoic acid
  • Methyl 2-thienyl ketone oxime
  • 2-(2,2-diisopropoxyacetyl)thiophene
  • isopropylamine
  • Diisopropylamine
  • 2-Nitropropane
  • t-butyl nitrite
  • Isopropanol
  • 1,3-Dichloro-5-nitrobenzene

Customs

[ HS Code ]: 2920909090

[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%


Related Compounds

  • ISOPROPYL LAUROYL SARCOSINATE
  • isopropyl peroxy radical
  • isopropyl 3-(1-(dimethylamino)-2-hydroxypropan-2-yl)-3-methyloxirane-2-carboxylate
  • isopropyl hydrogen maleate
  • isopropyl 3-(1-(diethylamino)-2-hydroxypropan-2-yl)-3-methyloxirane-2-carboxylate
  • isopropyl 2,2-dimethylbutanoate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 6-(indoline-1-carbonyl)-2-methyl-5,6,7,8-tetrahydrocinnolin-3(2H)-one
  • tert-Butyl-DL-alanine
  • N-((1r,4r)-4-((5-fluoropyrimidin-2-yl)oxy)cyclohexyl)-1-methyl-1H-imidazole-4-sulfonamide