Sodium polymethacrylate

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Names

[ CAS No. ]:
54193-36-1

[ Name ]:
Sodium polymethacrylate

[Synonym ]:
MFCD00156535

Chemical & Physical Properties

[ Density]:
1.023g/cm3

[ Boiling Point ]:
160.5ºC at 760mmHg

[ Molecular Formula ]:
C4H5NaO2

[ Molecular Weight ]:
108.07100

[ Flash Point ]:
74.2ºC

[ Exact Mass ]:
108.01900

[ PSA ]:
40.13000

[ Index of Refraction ]:
n20/D 1.401

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD3425900
CHEMICAL NAME :
2-Propenoic acid, 2-methyl-, homopolymer, sodium salt
CAS REGISTRY NUMBER :
54193-36-1
LAST UPDATED :
199701
DATA ITEMS CITED :
5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 18,146,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1409,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3905 No. of Facilities: 72046 (estimated) No. of Industries: 252 No. of Occupations: 117 No. of Employees: 562194 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9947 No. of Facilities: 10895 (estimated) No. of Industries: 134 No. of Occupations: 81 No. of Employees: 136472 (estimated) No. of Female Employees: 16000 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UD3425900

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A novel pH-dependant and double crosslinked polymethacrylate-based polysphere matrix for enteric delivery of isoniazid.

Pharm. Dev. Technol. 18(5) , 1066-77, (2013)

This study aimed at developing double crosslinked isoniazid (INH)-loaded polymethyl-methacrylate-ethylcellulose (PMMA-EC) polyspheres for rate-controlled enteric drug delivery. A PMMA solution was man...

Poly(methacrylic acid)-grafted chitosan microspheres via surface-initiated ATRP for enhanced removal of Cd(II) ions from aqueous solution.

J. Colloid. Interface Sci. 405 , 171-82, (2013)

Cross-linked chitosan (CCS) microspheres tethered with pH-sensitive poly(methacrylic acid) (PMAA) brushes were developed for the efficient removal of Cd(II) ions from aqueous solutions. Functional PMA...

Strain screening, fermentation, separation, and encapsulation for production of nattokinase functional food.

Appl. Biochem. Biotechnol. 168(7) , 1753-64, (2012)

This study presents a novel and integrated preparation technology for nattokinase functional food, including strain screening, fermentation, separation, and encapsulation. To rapidly screen a nattokin...


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