6-Hydroxy-3,4-dihydroquinolin-2(1H)-one

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Names

[ CAS No. ]:
54197-66-9

[ Name ]:
6-Hydroxy-3,4-dihydroquinolin-2(1H)-one

[Synonym ]:
3,4-Dihydro-6-hydroxyquinolin-2(1H)-one
6-hydroxy-1,2,3,4-tetrahydro-2-quinolinone
6-Hydroxy-3,4-dihydroquinolinone
4-tetrahydroquinoline
6-hydroxy-3,4-dihydro-carbostyril
6-HYDROXY-3,4-DIHYDROQUINOLONE
MFCD02179410
6-hydroxy-1,2,3,4-tetrahydroquinolin-2-one
The intermediate of Cilostazol
6-HQ
6-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone (6-Hydroxy-3,4-dihydro-2(1H)-quinolinone
6-Hydroxy-3,4-dihydro-1H-quinoline-2-one
Intermediate of Cilostazol
2(1H)-Quinolinone, 3,4-dihydro-6-hydroxy-
3,4-Dihydro-6-hydroxy-2(1H)-quinolinone
6-Hydroxy-3,4-dihydroquinolin-2(1H)-one
Q-2
3,4-Dihydro-2,6-quinolinediol
6-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline
6-HYDROXY-3,4-DIHYDROCARBSTYRIL
T66 BMVT&J HQ
6-Hydroxy-2-oxo-1
6-Hydroxy-3,4-dihydro-1H-quinolin-2-one
6-hydroxy-1,2,3,4-tetrahydro-2-oxoquinoline
6-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
424.5±45.0 °C at 760 mmHg

[ Melting Point ]:
236-240 °C

[ Molecular Formula ]:
C9H9NO2

[ Molecular Weight ]:
163.173

[ Flash Point ]:
210.5±28.7 °C

[ Exact Mass ]:
163.063324

[ PSA ]:
49.33000

[ LogP ]:
0.60

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-chloro-N-(4-hydroxyphenyl)propanamide
  • Aluminium chloride
  • 3-Chloro-N-(4-methoxy-phenyl)-propionamide
  • 3,4-Dihydroquinolin-2(1H)-one
  • 4-Aminophenol
  • p-Anisidine
  • 3-Chloropropanoyl chloride
  • 3-Chloro-N-(4-ethoxyphenyl)propanamide

DownStream

  • 6-hydroxy-3,4-dihydro-1H-quinoline-2-thione
  • 3,4-DIHYDRO-6-[4-[1-(TRANS-4-HYDROXYCYCLOHEXYL)-1H-TETRAZOL-5-YL]BUTOXY]-2(1H)-QUINOLINONE
  • trans-3,4-Dihydro-6-[4-[1-[4-(phenylmethoxy)cyclohexyl]-1H-tetrazol-5-yl]butoxy]-2(1H)-quinolinone
  • 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-1-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butyl]-3,4-dihydro-1H-quinolin-2-one
  • Cilostazol
  • 3,4-Dehydro Cilostazol
  • 6-Methoxy-3,4-dihydro-2(1H)-quinolinone
  • 7-(3-Bromopropoxy)-3,4-dihydroquinolin-2(1H)-one
  • 6-butoxy-3,4-dihydro-1H-quinolin-2-one
  • 6-phenylmethoxy-3,4-dihydro-1H-quinolin-2-one

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Related Compounds

  • 6-hydroxy-3,4-dihydroquinolin-2(1H)-one
  • 8-Bromo-6-hydroxy-3,4-dihydroquinolin-2(1H)-one
  • 6-Bromo-1-hydroxy-3,4-dihydroquinolin-2(1H)-one
  • 6-Acetyl-1-hydroxy-3,4-dihydroquinolin-2(1H)-one
  • 6-Chloro-1-hydroxy-3,4-dihydroquinolin-2(1H)-one
  • 3-hydroxy-3,4-dihydroquinolin-2(1H)-one