6-amino-2-methylheptan-2-ol,hydrochloride
Suppliers
Names
[ CAS No. ]:
543-15-7
[ Name ]:
6-amino-2-methylheptan-2-ol,hydrochloride
[Synonym ]:
6-hydroxy-6-methyl-2-heptylamine hydrochloride
Heptylon tropfen
6-amino-2-methyl-2-heptanol hydrochloride
Heptamyl tropfen
Coreptil
MFCD00013015
6-Amino-2-methyl-heptan-2-ol,Hydrochlorid
Delmiton
Arcor tropfen
Cardiosintol
Heptaminol HCl
Cortensor
EINECS 208-837-5
6-amino-2-methyl-heptan-2-ol,hydrochloride
heptaminol hydrochloride
Chemical & Physical Properties
[ Density]:
0.895g/cm3
[ Boiling Point ]:
250.1ºC at 760mmHg
[ Melting Point ]:
165-167 °C(lit.)
[ Molecular Formula ]:
C8H20ClNO
[ Molecular Weight ]:
181.70300
[ Flash Point ]:
105.1ºC
[ Exact Mass ]:
181.12300
[ PSA ]:
46.25000
[ LogP ]:
2.77710
[ Storage condition ]:
2-8℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ3240000
- CHEMICAL NAME :
- 2-Heptanol, 6-amino-2-methyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 543-15-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H19-N-O.Cl-H
- MOLECULAR WEIGHT :
- 181.74
- WISWESSER LINE NOTATION :
- ZY1&3XQ1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 28 ug/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Kidney, Ureter, Bladder - urine volume increased Skin and Appendages - sweating
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,178,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,178,1951
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,515,1970
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MJ3240000
[ HS Code ]:
2922199090
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 827(2) , 199-204, (2005)
A study of the metabolism of isometheptene, an antispasmodic drug, in man and comparison with heptaminol metabolism, is presented in this paper. Isometheptene and two metabolites were detected in huma...
Eur. J. Clin. Pharmacol. 37(1) , 37-40, (1989)
Changes in venous haemodynamics were studied after administration of a single dose of 3 g Heptaminol Adenosine Phosphate (HAP) to 30 subjects with primary varicose veins. Strain gauge plethysmography ...
Angiology 43(7) , 567-71, (1992)
The purpose of this study was to measure the variations of lymphatic flow. A noninvasive isotopic method was used to achieve a functional exploration of lymphatic circulation. Fifteen subjects were us...