(L)-Canavanine

Names

[ CAS No. ]:
543-38-4

[ Name ]:
(L)-Canavanine

[Synonym ]:
L-Canavanine
L-α-AMINO-γ-[GUANIDINOOXY]-N-BUTYRIC ACID

Chemical & Physical Properties

[ Density]:
1.61g/cm3

[ Boiling Point ]:
431.2ºC at 760mmHg

[ Melting Point ]:
184ºC

[ Molecular Formula ]:
C₅H₁₂N₄O₃

[ Molecular Weight ]:
176.17

[ Flash Point ]:
214.6ºC

[ Exact Mass ]:
176.09100

[ PSA ]:
134.45000

[ LogP ]:
0.09430

[ Index of Refraction ]:
1.602

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ES7002000

CHEMICAL NAME :: Butyric acid, 2-amino-4-(guanidinooxy)-, L-

CAS REGISTRY NUMBER :: 543-38-4

LAST UPDATED :: 199410

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H12-N4-O3

MOLECULAR WEIGHT :: 176.21

WISWESSER LINE NOTATION :: QVYZ2OMYZUM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5900 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - hamster Cells - not otherwise specified

DOSE/DURATION :: 2200 umol/L

REFERENCE :: JCLLAX Journal of Cellular Physiology. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.67- 1966- Volume(issue)/page/year: 75,129,1970

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
ES7002000

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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