4-(Methylsulfonyl)benzenecarboximidamide hydrochloride

Suppliers

Names

[ CAS No. ]:
5434-06-0

[ Name ]:
4-(Methylsulfonyl)benzenecarboximidamide hydrochloride

[Synonym ]:
4-methylsulfonylbenzenecarboximidamide,hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
386.3ºC at 760mmHg

[ Molecular Formula ]:
C8H11ClN2O2S

[ Molecular Weight ]:
234.70300

[ Flash Point ]:
187.5ºC

[ Exact Mass ]:
234.02300

[ PSA ]:
92.39000

[ LogP ]:
3.05700

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV6292000
CHEMICAL NAME :
Benzamidine, p-(methylsulfonyl)-, hydrochloride
CAS REGISTRY NUMBER :
5434-06-0
LAST UPDATED :
198806
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H10-N2-O2-S.Cl-H
MOLECULAR WEIGHT :
234.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,160,1945
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 2,523,1944
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
280 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,160,1945

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(Methylsulfanyl)benzonitrile
  • 4-Nitrobenzonitrile
  • 4-(Methylsulfonyl)benzonitrile

DownStream

Related Compounds

  • 4-{4-cyclopropyl-1H-pyrazolo[3,4-c]pyridin-1-yl}aniline
  • 2-[4-(4-methylphenyl)-1H-pyrazolo[3,4-c]pyridin-1-yl]ethan-1-ol
  • 2-{4-phenyl-1H-pyrazolo[3,4-c]pyridin-1-yl}ethan-1-ol
  • 4-{1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl}-1,2,3,6-tetrahydropyridine
  • 4-{1-tert-butyl-1H-pyrazolo[3,4-c]pyridin-4-yl}-1,2,3,6-tetrahydropyridine
  • 4-{1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl}piperidine
  • 4-{1-tert-butyl-1H-pyrazolo[3,4-c]pyridin-4-yl}piperidine
  • 3-{1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl}benzaldehyde
  • 2-(2-Methoxy-5-methylphenyl)prop-2-en-1-amine
  • 4-bromo-1-(2,3-dimethylphenyl)-1H-pyrazolo[3,4-c]pyridine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.