1-(4-propanoylpiperazin-1-yl)propan-1-one

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Names

[ CAS No. ]:
5436-89-5

[ Name ]:
1-(4-propanoylpiperazin-1-yl)propan-1-one

[Synonym ]:
1,4-Dipropionylpiperazine

Chemical & Physical Properties

[ Density]:
1.076g/cm3

[ Boiling Point ]:
384.2ºC at 760 mmHg

[ Molecular Formula ]:
C10H18N2O2

[ Molecular Weight ]:
198.26200

[ Flash Point ]:
179ºC

[ Exact Mass ]:
198.13700

[ PSA ]:
40.62000

[ LogP ]:
0.35300

[ Index of Refraction ]:
1.49

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6780000
CHEMICAL NAME :
Piperazine, 1,4-dipropionyl-
CAS REGISTRY NUMBER :
5436-89-5
BEILSTEIN REFERENCE NO. :
1571602
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H18-N2-O2
MOLECULAR WEIGHT :
198.30
WISWESSER LINE NOTATION :
T6N DNTJ AV2 DV2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,801,1968

Synthetic Route

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Precursor & DownStream

Precursor

  • 1-piperazin-1-ylpropan-1-one
  • Propanoyl chloride
  • Piperazine
  • ethene

DownStream

Related Compounds

  • 1-(4-propanoylpiperazin-1-yl)propan-1-one
  • 1-(4-dodecylnaphthalen-1-yl)propan-1-one
  • 1-(4-phenylpiperazin-1-yl)propan-1-one
  • 1-(4-methylsulfanylnaphthalen-1-yl)propan-1-one
  • 1-(4-(benzylamino)piperidin-1-yl)propan-1-one
  • 1-[4-(2-oxopropoxy)naphthalen-1-yl]propan-1-one