12S-HETE

Suppliers

Names

[ CAS No. ]:
54397-83-0

[ Name ]:
12S-HETE

[Synonym ]:
5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-, (5Z,8Z,10E,12S,14Z)-
MFCD00036916
12-HETE
(5Z,8Z,10E,12S,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic acid
12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
12(S)-HETE

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
487.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O3

[ Molecular Weight ]:
320.466

[ Flash Point ]:
262.8±25.2 °C

[ Exact Mass ]:
320.235138

[ PSA ]:
57.53000

[ LogP ]:
5.45

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.514

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

[ Hazard Codes ]:
F,Xi

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S7-S16-S26-S36

[ RIDADR ]:
UN 1170 3/PG 2

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

  • methyl pyridazine-3-carbimidate
  • 2(S)-[(tert-butyldiphenylsilyl)oxy]-4(Z)-decenal
  • [(tert-butyldiphenylsilyl)oxy]-2(E),6(Z)-decedienal
  • 6,6,6-trimethoxyhex-1-yne
  • O,O-Bicyclohexyl-1,1'-diyl thiosulphite
  • (3S,E)-5-bromo-3-((tetrahydro-2H-pyran-2-yl)oxy)pent-4-en-1-ol
  • (Z)-methyl 9-(trimethylsilyl)non-5-en-8-ynoate
  • methyl 9-(trimethylsilyl)nona-5,8-diynoate

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Lack of association of ALOX12 and ALOX15B polymorphisms with psoriasis despite altered urinary excretion of 12(S)-hydroxyeicosatetraenoic acid.

Br. J. Dermatol. 172(2) , 337-44, (2015)

Pro- and anti-inflammatory metabolites of arachidonic acid - eicosanoids - participate in skin homeostasis, affecting the growth and differentiation of keratinocytes. Alterations of 12-lipoxygenase (L...

Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.

J. Neurosci. 35(7) , 2927-41, (2015)

Axon degeneration is a programed process that takes place during development, in response to neuronal injury, and as a component of neurodegenerative disease pathology, yet the molecular mechanisms th...

MyD88-BLT2-dependent cascade contributes to LPS-induced interleukin-6 production in mouse macrophage.

Exp. Mol. Med. 47 , e156, (2015)

Endotoxic responses to bacterial lipopolysaccharide (LPS) are triggered by Toll-like receptor 4 (TLR4) and involve the production of inflammatory mediators, including interleukin-6 (IL-6), by macropha...


More Articles


Related Compounds

  • 12S-HHTrE
  • (12S)-9α,15:11β,12-Diepoxytrichothecan-13-ol
  • (12S)-12-Hydroxy-15-hexadecynoic acid
  • (12S,13S)-9-Deoxy-12,13-epoxy-12,13-dihydro-9-oxoleucomycin V=3,4''-diacetate
  • (12S,15S)-15-Hydroxy-11,16-dioxo-15,20-dihydrosenecionan-12-yl ac etate
  • (12S,15R)-15-Hydroxy-11,16-dioxo-15,20-dihydrosenecionan-12-yl ac etate
  • (3-Chlorophenyl)(4-(2-methyl-6-((4-methylpyridin-2-yl)amino)pyrimidin-4-yl)piperazin-1-yl)methanone
  • N-(1-(trifluoromethyl)piperidin-3-yl)acetamide
  • N-(1-(trifluoromethyl)pyrrolidin-3-yl)acetamide
  • 1-(6-phenylpyridazin-3-yl)cyclopropanecarboxylic acid
  • N-((1-(trifluoromethyl)piperidin-3-yl)methyl)acetamide
  • N-((1-(trifluoromethyl)pyrrolidin-2-yl)methyl)acetamide
  • 2-(1-bromoethyl)-1-cyclopropyl-1H-imidazole
  • [1-(6-phenylpyridazin-3-yl)cyclopropyl]methanamine
  • 2-methyl-2-(6-phenylpyridazin-3-yl)propan-1-amine
  • [1-(6-methylpyrimidin-4-yl)cyclopropyl]methanamine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.