N,N′-2,6-PYRIDINEDIYLBISACETAMIDE

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Names

[ CAS No. ]:
5441-02-1

[ Name ]:
N,N′-2,6-PYRIDINEDIYLBISACETAMIDE

[Synonym ]:
Pyridine,2,6-diacetamido
2,6-di(acetylamino)pyridine
Acetamide,N,N'-2,6-pyridinediylbis
N,N'-(pyridine-2,6-diyl)diacetamide
SN 3,363
N,N'-pyridine-2,6-diylbis(acetylamide)
N,N'-2,6-Pyridinediylbisacetamide
2,6-N,N-Diacetyldiaminopyridine
2,6-Diacetamidopyridine
2,6-bis(methylcarbonylamino)pyridine

Chemical & Physical Properties

[ Molecular Formula ]:
C9H11N3O2

[ Molecular Weight ]:
193.20300

[ Exact Mass ]:
193.08500

[ PSA ]:
71.09000

[ LogP ]:
1.14440

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC7849500
CHEMICAL NAME :
Acetamide, N,N'-2,6-pyridinediylbis-
CAS REGISTRY NUMBER :
5441-02-1
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H11-N3-O2
MOLECULAR WEIGHT :
193.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
375 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
46800 mg/kg/30D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
600 mg/kg/6D-I
TOXIC EFFECTS :
Behavioral - food intake (animal) Kidney, Ureter, Bladder - hematuria Blood - changes in erythrocyte (RBC) count
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,6-Diaminopyridine
  • Acetyl chloride
  • Ethanoic anhydride
  • N-(6-Aminopyridin-2-yl)acetamid
  • Ethyl 2-methylacetoacetate
  • Ethyl trifluoroacetoacetate
  • Ethyl 3-oxo-3-phenylpropanoate
  • Ethyl 2-Chloroacetoacetate
  • Ethyl 3-oxohexanoate

DownStream

  • 3-Bromo-2,6-pyridinediamine
  • 2,6-Diaminopyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N,N,2,6-tetramethyl-4-nitroaniline
  • N,N,2,6-tetraethylaniline
  • 35DIMETHYL4DIMETHYLAMINOAZOBENZENE
  • H2tfpbbp
  • N-(2,6-Dimethylphenyl)azetidine
  • N,N′-DICHLOROBIS(2,4,6-TRICHLOROPHENYL) UREA
  • 8-Bromo-1-naphthalenepropanenitrile
  • 2-Chloro-1-(6,8-difluoro-3,4-dihydro-2H-quinolin-1-yl)ethanone
  • 5-[(Cyclobutylamino)methyl]-1-methyl-1H-imidazole-2-carbonitrile
  • 3-Fluoro-6-methoxy-2-(methylthio)benzoic acid
  • 1-(3-Amino-2-(chloromethyl)phenyl)-3-chloropropan-2-one
  • 1-(2-Amino-6-(chloromethyl)phenyl)-3-chloropropan-2-one
  • Ethyl(4-hydroxyphenyl)imino-lambda6-sulfanone
  • 2-Propanone, 1-[2-(2-furanyl)-4-thiazolyl]-
  • Phenyl-2-piperidinylmethanone hydrazone
  • 5-Benzyl-1-methylimidazole-2-carbaldehyde