URB597

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Names

[ CAS No. ]:
546141-08-6

[ Name ]:
URB597

[Synonym ]:
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester
URB597
3'-Carbamoyl-3-biphenylyl cyclohexylcarbamate
Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester
3'-Carbamoylbiphenyl-3-yl cyclohexylcarbamate
Cyclohexyl-carbamic acid 3'-carbamoyl-biphenyl-3-yl ester
[3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
3'-(aminocarbonyl)-1,1'-biphenyl-3-yl cyclohexylcarbamate
URB-597

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
533.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H22N2O3

[ Molecular Weight ]:
338.400

[ Flash Point ]:
276.3±30.1 °C

[ Exact Mass ]:
338.163055

[ PSA ]:
81.42000

[ LogP ]:
3.51

[ Appearance of Characters ]:
powder | white

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.618

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: ~14 mg/mL, soluble

MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H410

[ Precautionary Statements ]:
P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
22-24/25-60-61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.

Neurobiol. Dis. 74 , 295-304, (2015)

Long-term administration of l-3,4-dihydroxyphenylalanine (levodopa), the mainstay treatment for Parkinson's disease (PD), is accompanied by fluctuations in its duration of action and motor complicatio...

Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies.

Neurobiol. Dis. 79 , 41-50, (2015)

Anandamide (AEA) is an endocannabinoid (EC) that modulates multiple functions in the CNS and that is released in areas of injury, exerting putative neuroprotective actions. In the present study, we ha...

Correlating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: from ultrapotent to hyperpotent.

Biochem. Pharmacol. 92(4) , 669-89, (2014)

Besides the suggested role of a putative endocannabinoid membrane transporter mediating the cellular uptake of the endocannabinoid anandamide (AEA), this process is intrinsically coupled to AEA degrad...


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Related Compounds

  • URB 937
  • Pyrromethene 597
  • FRAX 597
  • 5-ethyl-3-[[2-fluoro-4-[2-(3-methylbutoxycarbonylsulfamoyl)phenyl]phenyl]methyl]-2-propylimidazole-4-carboxylic acid
  • ucb 597
  • Anthra[2,1,9-mna]naphth[2,3-h]acridin-5(16H)-one, 3-[[9,10-bis(sulfooxy)-1-anthracenyl]amino]-10,15-bis(sulfooxy)-, chlorinated cyclized