3-[(2-methyl-1H-indol-3-yl)methyl]-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione

Names

[ CAS No. ]:
54648-99-6

[ Name ]:
3-[(2-methyl-1H-indol-3-yl)methyl]-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
519.7ºC at 760 mmHg

[ Molecular Formula ]:
C19H18N4S

[ Molecular Weight ]:
334.43800

[ Flash Point ]:
268.1ºC

[ Exact Mass ]:
334.12500

[ PSA ]:
85.30000

[ LogP ]:
4.24490

[ Index of Refraction ]:
1.708

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ5359130
CHEMICAL NAME :
3H-1,2,4-Triazole-3-thione, 2,4-dihydro-5-((2-methyl-1H-indol-3-yl)methyl)-4- (2-methylphenyl)-
CAS REGISTRY NUMBER :
54648-99-6
LAST UPDATED :
198512
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H18-N4-S
MOLECULAR WEIGHT :
334.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
CNJPAZ Canadian Journal of Pharmaceutical Sciences. (Toronto, Ont., Canada) V.1-16, 1966-81. Discontinued. Volume(issue)/page/year: 9,108,1974

Related Compounds

  • methyl 3-(methoxymethyl)-3,6-dihydro-2H-pyran-3-carboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-[(3-Fluoro-2,6-dimethoxyphenyl)methyl]azetidine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-Methoxy-1-{4-[(methylamino)methyl]-1,3-thiazol-2-yl}propan-1-ol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3,5-diethyl 4-(1-cyclohexyl-1H-1,2,3-triazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate