Methyl isobutyrate

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Names

[ CAS No. ]:
547-63-7

[ Name ]:
Methyl isobutyrate

[Synonym ]:
EINECS 208-929-5
Propanoic acid, 2-methyl-, methyl ester
MFCD00008914
Methyl isobutyrate
Methyl 2-methylpropanoate

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
93.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-85--84 °C

[ Molecular Formula ]:
C5H10O2

[ Molecular Weight ]:
102.132

[ Flash Point ]:
3.3±0.0 °C

[ Exact Mass ]:
102.068077

[ PSA ]:
26.30000

[ LogP ]:
1.06

[ Vapour Pressure ]:
50.4±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.385

[ Water Solubility ]:
slightly soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NQ5425000
CHEMICAL NAME :
Isobutyric acid, methyl ester
CAS REGISTRY NUMBER :
547-63-7
BEILSTEIN REFERENCE NO. :
1740720
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H10-O2
MOLECULAR WEIGHT :
102.15
WISWESSER LINE NOTATION :
1Y1&VO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25500 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,84,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4031 No. of Facilities: 11 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 22 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4031 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 45 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H332

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;Xi:Irritant;

[ Risk Phrases ]:
R11;R36/37/38

[ Safety Phrases ]:
S16-S37/39-S26

[ RIDADR ]:
UN 1237 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
NQ5425000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2915900090

Synthetic Route

Precursor & DownStream

Precursor

  • Methanol
  • 2,2-DIBROMOPROPANE
  • carbon monoxide
  • Methyl methacrylate
  • O-methyl selenoisobutirate
  • Isobutyraldehyde
  • Ethanoic anhydride
  • 4-Methyl-2-pentanone
  • propene

DownStream

  • methyl 4-chloro-2,2-dimethylbutanoate
  • Dimethyl dimethylmalonate
  • 3-Cyclopenten-1-ol,3,4-dimethyl-1-(1-methylethyl)-(9CI)
  • 2-Isobutyrylcyclohexanone
  • methyl 2-methyl-2-naphthalen-2-ylpropanoate
  • ISOBUTYROHYDROXAMIC ACID
  • methyl 2-chloro-2-methylpropanoate
  • Isobutyric acid hydrazide
  • Methyl methacrylate
  • isobutanol

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Mass spectrometry of and deposition-rate measurements from radiofrequency-induced plasmas of methyl isobutyrate, methyl methacrylate and n-butyl methacrylate. O'Toole L, et al.

J. Chem. Soc., Faraday 91(9) , 1363-70, (1995)

Penetrant diffusion in poly (methyl methacrylate) near Tg: dependence on temperature and polymer weight fraction. Tonge MP, et al.

Polymer 41(10) , 3659-70, (2000)


More Articles


Related Compounds

  • methyl isobutyrate
  • methyl isobutyrate-2-yl
  • 2-iodo methyl isobutyrate
  • 3-cyano methyl isobutyrate
  • 2-chloro methyl isobutyrate
  • methanol,methyl isobutyrate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-Cyclopropoxy-N5,N5-dimethylpyridine-2,5-diamine
  • tert-butyl N-(2-bromocyclopentyl)carbamate
  • Methanone,(3,4-dichlorophenyl)[6,7-dihydro-4-(4-Methylphenyl)thieno[3,2-c]pyridin-5(4H)-yl]-
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • tert-Butyl 2-((quinoxalin-2-ylsulfinyl)methyl)pyrrolidine-1-carboxylate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide