1,4-Piperazinedicarboxylicacid, 1,4-diethyl ester

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Names

[ CAS No. ]:
5470-28-0

[ Name ]:
1,4-Piperazinedicarboxylicacid, 1,4-diethyl ester

[Synonym ]:
piperazine-1,4-dicarboxylic acid diethyl ester
Piperazin-1,4-dicarbonsaeure-diaethylester
1,4-Dicarbethoxy piperazine
1,4-Piperazinedicarboxylic acid,diethyl ester
Diethyl 1,4-piperazinedicarboxylate

Chemical & Physical Properties

[ Density]:
1.169g/cm3

[ Boiling Point ]:
315ºC at 760mmHg

[ Molecular Formula ]:
C10H18N2O4

[ Molecular Weight ]:
230.26100

[ Flash Point ]:
144.3ºC

[ Exact Mass ]:
230.12700

[ PSA ]:
59.08000

[ LogP ]:
0.79280

[ Index of Refraction ]:
1.488

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL3550000
CHEMICAL NAME :
1,4-Piperazinedicarboxylic acid, diethyl ester
CAS REGISTRY NUMBER :
5470-28-0
BEILSTEIN REFERENCE NO. :
0216109
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H18-N2-O4
MOLECULAR WEIGHT :
230.30
WISWESSER LINE NOTATION :
T6N DNTJ AVO2 DVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Carbethoxy Piperazine
  • S-ethoxycarbonyl 4-methyl-1-piperazinecarbodithioate
  • Piperazine
  • Ethyl chloroformate

DownStream

  • N,N'-Dimethylpiperazine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1,4-Piperazinedicarboxylicacid, 2-methyl-, 1,4-diethyl ester
  • 1,4-Cyclohexanedicarboxylicacid, 1,4-diethyl ester
  • 1,4-Benzenedicarboximidicacid, 1,4-diethyl ester, hydrochloride (1:2)
  • 1,4-Piperazinedicarboxylicacid, 1,4-bis(1-methylethyl) ester
  • 1,4-Cyclohexanedicarboxylicacid, 2,5-dihydroxy-, 1,4-diethyl ester
  • 1,4-Benzenedicarboxylicacid, 2,5-diamino-, 1,4-diethyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-Amino-2-(1-methylcyclohexyl)acetic acid hydrochloride
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2,3-Dihydro-N-(4-methylcyclohexyl)-1,4-benzodioxin-6-ethanamine
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Methyl 4-[({[3-ethyl-7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]thio}acetyl)amino]benzoate