1H-Pyrido[3,4-b]indole-3-carboxylicacid, 2,3,4,9-tetrahydro-1-methyl-

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Names

[ CAS No. ]:
5470-37-1

[ Name ]:
1H-Pyrido[3,4-b]indole-3-carboxylicacid, 2,3,4,9-tetrahydro-1-methyl-

[Synonym ]:
IFLAB-BB F1918-0045
MTCA
1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid
1,2,3,4-TETRAHYDROHARMAN-3-CARBOXYLIC ACID
1,2,3,4-TETRAHYDROHARMANE-3-CARBOXYLIC ACID
MFCD00022199
AURORA 764
Tetrahydroharman-3-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.301g/cm3

[ Boiling Point ]:
488ºC at 760mmHg

[ Molecular Formula ]:
C13H14N2O2

[ Molecular Weight ]:
230.26200

[ Flash Point ]:
248.9ºC

[ Exact Mass ]:
230.10600

[ PSA ]:
65.12000

[ LogP ]:
2.15660

[ Index of Refraction ]:
1.697

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 1544

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Precursor & DownStream

Precursor

  • ch3cho
  • L(-)-Tryptophan
  • DL-Tryptophan
  • Methylglyoxal

DownStream

  • Harmane
  • 1-methyl-3,4-dihydro-beta-carboline-3-carboxylic acid
  • (1-methyl-9H-pyrido[3,4-b]indol-3-yl)methanol
  • 1-Methyl-β-carboline-3-carboxylic acid methyl ester

Articles

Identification and mode of action of 5-hydroxymethyl-2-furfural (5-hmf) and 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) as potent xanthine oxidase inhibitors in vinegars.

J. Agric. Food Chem. 60(39) , 9856-62, (2012)

Vinegars have been used as an alternative remedy for treating gout, but the scientific basis remains to be elucidated. In this study, seven commercial vinegars and one laboratory-prepared red-koji vin...

1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid and 1,2, 3,4-tetrahydro-beta-carboline-3-carboxylic acid in fruits.

J. Agric. Food Chem. 47(12) , 4883-7, (1999)

1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid (THCA) and 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid (MTCA), as two diastereoisomers (1S,3S and 1R,3S), occurred in commercial fr...

Acute cytogenetic effects of tyramine, MTCAs, NaCl and soy sauce on rat bone marrow cells in vivo.

Mutat. Res. 240(4) , 281-8, (1990)

The acute cytogenetic effects of tyramine and MTCAs, precursors of the mutagen present in soy sauce, were studied with the in vivo chromosome aberration test in rat bone marrow cells. The chemicals we...


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