1-(3-Chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-methyl-1H-pyrazole-3-carboxamide

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Names

[ CAS No. ]:
54708-76-8

[ Name ]:
1-(3-Chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-methyl-1H-pyrazole-3-carboxamide

[Synonym ]:
pz-250

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
529ºC at 760 mmHg

[ Molecular Formula ]:
C14H16ClN3O3

[ Molecular Weight ]:
309.74800

[ Flash Point ]:
273.7ºC

[ Exact Mass ]:
309.08800

[ PSA ]:
67.59000

[ LogP ]:
1.59860

[ Index of Refraction ]:
1.595

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ6310000
CHEMICAL NAME :
1H-Pyrazole-3-carboxamide, 1-(3-chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-met hyl-
CAS REGISTRY NUMBER :
54708-76-8
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H16-Cl-N3-O3
MOLECULAR WEIGHT :
309.78
WISWESSER LINE NOTATION :
T5NNJ AR CG& CVN1&2Q EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
460 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 25,781,1975

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 7-(Difluoromethyl)-2-(pentan-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide