4-(4-Hydroxyphenyl)-2-butanone

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Names

[ CAS No. ]:
5471-51-2

[ Name ]:
4-(4-Hydroxyphenyl)-2-butanone

[Synonym ]:
Oxyphenalon
4-hydroxy benzyl acetone
Raspberry keton
4-(4-Hydroxyphenyl)-2-butanone
Frambinone
Rheosmin
OXYPHENONE
OXYPHENYLON
Raspberry ketone
EINECS 226-806-4
RASBERRY KETONE
MFCD00002394
p-Hydroxy benzylacetone
FEMA 2588
OXANONE

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
292.2±15.0 °C at 760 mmHg

[ Melting Point ]:
81-85 °C(lit.)

[ Molecular Formula ]:
C10H12O2

[ Molecular Weight ]:
164.201

[ Flash Point ]:
122.9±13.0 °C

[ Exact Mass ]:
164.083725

[ PSA ]:
37.30000

[ LogP ]:
0.94

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.535

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL8925000
CHEMICAL NAME :
2-Butanone, 4-(p-hydroxyphenyl)-
CAS REGISTRY NUMBER :
5471-51-2
BEILSTEIN REFERENCE NO. :
0776080
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H12-O2
MOLECULAR WEIGHT :
164.22
WISWESSER LINE NOTATION :
QR D2V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1320 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - analgesia
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 8,349,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - analgesia
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 8,349,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4912 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 3245 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4912 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
EL8925000

[ HS Code ]:
2914501100

Precursor & DownStream

Precursor

  • 4-(4-((triisopropylsilyl)oxy)phenyl)butan-2-one
  • Methyl vinyl ketone
  • Phenol
  • (E)-4-(4-Hydroxyphenyl)but-3-en-2-one
  • (+)-Rhododendrol
  • 4-hydroxybenzaldehyde
  • Acetone
  • 4-Hydroxy-2-butanone
  • 3-Buten-2-ol
  • 4-Iodophenol

DownStream

  • 2-[4-(3-hydroxy-3-methylbutyl)phenoxy]acetic acid
  • p-Methoxybenzylacetone
  • Raspberryketone glucoside
  • Cuelure
  • 4-Butylphenol
  • 4-(3-oxobutyl)phenyl benzoate
  • Benzenepropanol, 4-hydroxy-.alpha.,.alpha.-dimethyl-
  • 2,3-Butanedione,1-(4-hydroxyphenyl)-, 2-oxime
  • 4-(4-trimethylsilyloxyphenyl)butan-2-one

Customs

[ HS Code ]: 2914501100

[ Summary ]:
HS: 2914501100. 4-(4-hydroxyphenyl)butan-2-one. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:5.5%. general tariff:30.0%

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Related Compounds

  • 4-(4-hydroxyphenyl)-2,3-diphenylbicyclo[3.3.1]non-3-en-9-one
  • 4-(4-Hydroxyphenyl)-2-methylpentan-2-ylcarbamate
  • 4-(4-hydroxyphenyl)-2-methylphenol
  • 4-(4-hydroxyphenyl)-2,4,5,10-tetrahydro-1H-pyrrolo[3,4-c][1,5]benzodiazepin-3-one
  • 4-(4-hydroxyphenyl)-2-nitrobenzoic acid
  • 4-(4-hydroxyphenyl)-2-nitrophenol
  • {1-Azaspiro[4.4]nonan-3-yl}(imino)methyl-lambda6-sulfanone
  • 2-Fluoro-4-{[(prop-2-en-1-yloxy)carbonyl]amino}but-2-enoic acid
  • (2S)-3-(1,3-dioxolan-2-yl)-2-acetamidopropanoic acid
  • tert-butyl N-[2-amino-1-(1-phenyl-1H-1,2,3-triazol-4-yl)ethyl]carbamate
  • tert-butyl N-[3-amino-2-(2-chloro-1-benzofuran-3-yl)-2-methylpropyl]carbamate
  • tert-butyl N-[4-(2-amino-1,3-thiazol-4-yl)-3-fluorophenyl]carbamate
  • tert-butyl N-{3-fluoro-4-[(sulfamoyloxy)methyl]phenyl}carbamate
  • tert-butyl N-[1-(2,6-dichlorophenyl)-2-oxoethyl]carbamate
  • (2S)-4-hydroxy-2-{methyl[(prop-2-en-1-yloxy)carbonyl]amino}butanoic acid
  • 2-[4-Acetyl-6-(hydroxymethyl)morpholin-2-yl]acetic acid
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