iodoacetic anhydride

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Names

[ CAS No. ]:
54907-61-8

[ Name ]:
iodoacetic anhydride

[Synonym ]:
MFCD00001080
Acetic acid,2-iodo-,1,1'-anhydride
Acetic acid,iodo-,anhydride
Iodoacetic anhydride
iodoacetic acid anhydride
iodoacetyl anhydride
Jod-essigsaeure-anhydrid

Chemical & Physical Properties

[ Density]:
2.664g/cm3

[ Boiling Point ]:
276.9ºC at 760 mmHg

[ Melting Point ]:
47-49ºC(lit.)

[ Molecular Formula ]:
C4H4I2O3

[ Molecular Weight ]:
353.88200

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
353.82500

[ PSA ]:
43.37000

[ LogP ]:
0.92620

[ Appearance of Characters ]:
Crystalline Powder | Yellow

[ Index of Refraction ]:
1.647

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
chloroform: soluble10%, clear to slightly hazy, yellow (pink or tan)

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H314

[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,C

[ Risk Phrases ]:
25-35

[ Safety Phrases ]:
22-36/37/39-45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ HS Code ]:
2915900090

Synthetic Route

Precursor & DownStream

Precursor

  • Iodoacetic acid
  • IODOACETYL CHLORIDE
  • Thionyl chloride

DownStream

  • Iodoacetamide
  • 4-[(2-iodoacetyl)amino]benzoic acid

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and evaluation of nuclear targeting peptide-antisense oligodeoxynucleotide conjugates.

Bioconjug. Chem. 6(1) , 101-8, (1995)

An endogenous nuclear enzyme, RNase H, is an important component in determining the efficacy of antisense oligodeoxynucleotides (ODNs). In an effort to improve the potency of antisense ODNs, conjugate...

A novel method for the incorporation of glycoprotein-derived oligosaccharides into neoglycopeptides.

Bioconjug. Chem. 3(5) , 391-6, (1992)

We describe a new method for the transfer of carbohydrate moieties to polypeptides in which complex carbohydrate, in the form of glycosyl amino acid, is removed from an available glycoprotein, derivat...

Peptide affinity chromatography media that bind N(pro) fusion proteins under chaotropic conditions.

J. Chromatogr. A. 1217(40) , 6203-13, (2010)

To design a generic purification platform and to combine the advantages of fusion protein technology and matrix-assisted refolding, a peptide affinity medium was developed that binds inclusion body-de...


More Articles


Related Compounds

  • iodoacetic anhydride
  • iodoacetic acid, [2-14c]
  • iodoacetic acid, [3h]
  • Iodoacetic acid 2-hydroxyethyl ester
  • IODOACETIC ACID-D3
  • Iodoacetic acid-2-13C
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (Z)-But-2-en-1-ylboronic acid
  • 2-Pyridinecarboxamide, N-(3-((4R)-2-amino-5,5-difluoro-5,6-dihydro-4-methyl-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyano-, hydrochloride (1:1)
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-[(15-Tert-butoxycarbonylpentadecanoylamino)methyl]benzoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde