1-phenylbiguanide hydrochloride

Suppliers

Names

[ CAS No. ]:
55-57-2

[ Name ]:
1-phenylbiguanide hydrochloride

[Synonym ]:
Phenylbiguanide monohydrochloride
Phenylbiguanide hydrochloride
1-phenylbiguanide hydrochloride
MFCD00035040
N-phenylbiguanide hydrochloride
Phenyldiguanide hydrochloride
EINECS 200-239-2
N'-Phenylbiguanide monohydrochloride
N-phenylimidodicarbonimidic diamide hydrochloride
1-Phenylbiquanide hydrochloride
1-Phenylbiguanide monohydrochloride
1-phenyl-biguanidium chloride
1-phenyl-biguanide hydrogenchloride

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
388.4ºC at 760mmHg

[ Melting Point ]:
244-247ºC(lit.)

[ Molecular Formula ]:
C8H12ClN5

[ Molecular Weight ]:
213.66700

[ Flash Point ]:
188.7ºC

[ Exact Mass ]:
213.07800

[ PSA ]:
97.78000

[ LogP ]:
2.68200

[ Storage condition ]:
Store at RT

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU2550000
CHEMICAL NAME :
Biguanide, 1-phenyl-, monohydrochloride
CAS REGISTRY NUMBER :
55-57-2
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H11-N5.Cl-H
MOLECULAR WEIGHT :
213.70
WISWESSER LINE NOTATION :
MUYZMYUM&MR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 1,434,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
243 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,117,1974

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DU2550000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Anilinium chloride

DownStream

  • 1,3,5-Triazine-2,4-diamine,6-(chloromethyl)-N2-phenyl-
  • 6-METHYL-N-PHENYL-1,3,5-TRIAZINE-2,4-DIAMINE
  • Amanozine

Articles

Indian red scorpion venom-induced augmentation of cardio-respiratory reflexes and pulmonary edema involve the release of histamine.

Toxicon 57(2) , 193-8, (2011)

Pulmonary edema is a consistent feature of Mesobuthus tamulus (MBT) envenomation. Kinins, prostaglandins and other inflammatory mediators are implicated in it. Since, histamine also increases capillar...

Effect of 3,5-dicarbomethoxyphenylbiguanide on free radical homeostasis in rats with experimental myocarditis.

Bull. Exp. Biol. Med. 154(2) , 192-5, (2012)

Administration of 3,5-dicarbomethoxyphenylbiguanide to rats with experimental epinephrine-induced myocarditis was followed by a decrease in activity of marker enzymes for cardiomyocyte cytolysis in th...

B(2) kinin receptors mediate the Indian red scorpion venom-induced augmentation of visceral reflexes via the nitric oxide cyclic guanosine monophosphate pathway.

Acta Physiol. (Oxf.) 196(4) , 365-73, (2009)

This study was performed to delineate the kinin (receptor)-dependent pathways in the Indian red scorpion (Mesobuthus tamulus; MBT) venom-induced pulmonary oedema as well as the augmentation of cardio-...


More Articles

Related Compounds

  • 1-phenylbiguanide hydrochloride
  • 1-Phenylbiguanide hydrochloride
  • 1-(4-trifluoromethyl)phenylbiguanide hydrochloride
  • (+)-3R-N-Monomethylamino-4c-phenyl-4t-ethoxycarbonylcyclohexene-1, hydrochloride
  • 2-(3,5-dichlorophenyl)-2-phenylethanamine,hydrochloride
  • 1-Decanamine,hydrochloride (1:1)
  • 1-[2-(5,6-Dichloropyridin-3-yl)ethyl]cyclopropan-1-amine
  • 2-Fluoro-1-(isoquinolin-5-yl)ethan-1-ol
  • 5-(5-Bromo-2-chlorophenyl)-1,3-oxazol-2-amine
  • 1-Amino-4,4-diethylhexan-3-ol
  • (2R)-1-(6-chloropyridin-2-yl)propan-2-amine
  • 1-[1-(3,3-Difluorocyclobutyl)cyclopropyl]ethan-1-ol
  • 4-Methoxy-3-methylpyridin-2-aminehydrochloride
  • O-[1-(1-ethenyl-1H-pyrazol-4-yl)ethyl]hydroxylamine
  • 5-Azido-2-methyl-3-(sulfanylmethyl)benzaldehyde
  • 4-Formyl-3-(propan-2-yloxy)benzoic acid
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