hydrocotarnine

Suppliers

Names

[ CAS No. ]:
550-10-7

[ Name ]:
hydrocotarnine

[Synonym ]:
8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline
Hydrocotarnine

Chemical & Physical Properties

[ Boiling Point ]:
342.4ºC at 760 mmHg

[ Molecular Formula ]:
C12H15NO3

[ Molecular Weight ]:
221.25200

[ Flash Point ]:
106.7ºC

[ Exact Mass ]:
221.10500

[ PSA ]:
30.93000

[ LogP ]:
1.34970

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JI4825000
CHEMICAL NAME :
1,3-Dioxolo(4,5-g)isoquinoline, 5,6,7,8-tetrahydro-4-methoxy-6-methyl-
CAS REGISTRY NUMBER :
550-10-7
BEILSTEIN REFERENCE NO. :
0017283
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H15-N-O3
MOLECULAR WEIGHT :
221.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 15,111,1960
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 15,111,1960

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 8-Methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-ol
  • Acetic acid 8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-yl ester
  • 5,6,7,8-Tetrahydro-8-ethoxy-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinoline
  • N-(2-methoxy-3,4-methylenedioxybenzyl)-N-(p-toluene-sulfonyl)aminoacetaldehyde diethylacetal
  • 4-Methoxy-1,3-benzodioxole-5-carbaldehyde
  • [N-[2-Methoxy-3,4-(methylenedioxy)benzyl]amino]acetaldehyde diethyl acetal
  • [N-[2-Methoxy-3,4-(methylenedioxy)benzyl]-N-methylamino]acetaldehyde diethyl acetal
  • cotarnine
  • 1,3-dimethylbarbituric acid

DownStream

  • 4-methoxy-6-methyl-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium,iodide
  • Meconine
  • 2-Methyl-1,2,3,4-tetrahydroisoquinolin-6-ol
  • 2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
  • 1,3-Dioxolo[4,5-g]isoquinoline, 5,6,7, 8-tetrahydro-6-methyl-

Related Compounds

  • Hydrocotarnine HCl
  • Hydrocotarnine methiodide
  • Hydrocotarnine hydriodide
  • Hydrocotarnine hemihydrate
  • Hydrocotarnine methobromide
  • Hydrocotarnine hydrobromide
  • 5-(1,2-oxazol-4-yl)-4-propyl-4H-1,2,4-triazole-3-sulfonyl fluoride
  • 5-(2-methoxypropan-2-yl)-4-propyl-4H-1,2,4-triazole-3-sulfonyl fluoride
  • 5-[(1R,2S)-1-amino-2-hydroxypropyl]-4-cyclopropyl-4H-1,2,4-triazole-3-sulfonyl fluoride
  • 4-cyclopropyl-5-(2-methylbutyl)-4H-1,2,4-triazole-3-sulfonyl fluoride
  • 1-(2,3-dihydro-1H-inden-5-yl)ethane-1-sulfonyl fluoride
  • (1-ethyl-3-methyl-1H-pyrazol-4-yl)methanesulfonyl fluoride
  • [1-(3-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]methanesulfonyl fluoride
  • [3-methyl-1-(pyrazin-2-yl)-1H-pyrazol-4-yl]methanesulfonyl fluoride
  • [1-(butan-2-yl)-3-methyl-1H-pyrazol-4-yl]methanesulfonyl fluoride
  • [3-methyl-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazol-4-yl]methanesulfonyl fluoride
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.