Amisometradine

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Names

[ CAS No. ]:
550-28-7

[ Name ]:
Amisometradine

[Synonym ]:
Aminoisometradin
6-Amino-1-metallyl-3-methylpyrimidine-2,4-dione
AMISOMETRADINE
Aminoisometradine
Amisometradin
Rolicton
6-Amino-1-methallyl-3-methyl-1H-pyrimidin-2,4-dion
Amisometradinum [INN-Latin]
6-Amino-3-methyl-1-(2-methylallyl)uracil
Uracil,6-amino-3-methyl-1-(2-methylallyl)
6-amino-1-methallyl-3-methyl-1H-pyrimidine-2,4-dione
6-amino-3-methyl-1-(2-methyl-allyl)-1H-pyrimidine-2,4-dione
Amisometradina [INN-Spanish]

Chemical & Physical Properties

[ Density]:
1.176g/cm3

[ Boiling Point ]:
292.1ºC at 760 mmHg

[ Molecular Formula ]:
C9H13N3O2

[ Molecular Weight ]:
195.21800

[ Flash Point ]:
130.5ºC

[ Exact Mass ]:
195.10100

[ PSA ]:
70.02000

[ LogP ]:
0.28650

[ Index of Refraction ]:
1.537

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ8800000
CHEMICAL NAME :
Uracil, 6-amino-3-methyl-1-(2-methylallyl)-
CAS REGISTRY NUMBER :
550-28-7
BEILSTEIN REFERENCE NO. :
0182347
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H13-N3-O2
MOLECULAR WEIGHT :
195.25
WISWESSER LINE NOTATION :
T6NVNVJ A1Y1&U1 C1 FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
515 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
610 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
415 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Precursor & DownStream

Precursor

  • N-cyanoacetyl-N'-methallyl-urea
  • Dimethyl sulfate

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 1-Isopropyl-3-((1r,4r)-4-(pyridin-2-yloxy)cyclohexyl)urea
  • N-((1r,4r)-4-((5-fluoropyrimidin-2-yl)oxy)cyclohexyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide