Propoxycaine (hydrochloride)

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Names

[ CAS No. ]:
550-83-4

[ Name ]:
Propoxycaine (hydrochloride)

[Synonym ]:
Pravocaine hydrochloride
EINECS 208-988-7
WIN 3459
Propoxycaine HCl
Ravocaine hydrochloride
Blockain
4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
BENZOIC ACID,4-AMINO-2-PROPOXY-,2-(DIETHYLAMINO)ETHYL ESTER,MONOHYDROCHLORIDE
Propoxycaine Hyrochloride
Propoxycaine hydrochloride
Propoxycaine (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
434.4ºC at 760mmHg

[ Molecular Formula ]:
C16H27ClN2O3

[ Molecular Weight ]:
330.85000

[ Flash Point ]:
216.5ºC

[ Exact Mass ]:
330.17100

[ PSA ]:
64.79000

[ LogP ]:
3.93940

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG3066000
CHEMICAL NAME :
Benzoic acid, 4-amino-2-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride
CAS REGISTRY NUMBER :
550-83-4
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H26-N2-O3.Cl-H
MOLECULAR WEIGHT :
330.90
WISWESSER LINE NOTATION :
3OR CZ FVO2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7417 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958

Safety Information

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 2-Propyl-4H-1,3-benzothiazine
  • 3-(3-Bromo-5-chlorophenyl)-3-hydroxypropanoic acid
  • 5-[(3-methoxyazetidin-3-yl)methyl]-1H-indole
  • [3-(1H-indol-4-yl)-2,2-dimethylcyclopropyl]methanamine
  • O-[1-(2,4,5-trifluorophenyl)propan-2-yl]hydroxylamine
  • O-[2-methyl-3-(2,4,5-trifluorophenyl)propyl]hydroxylamine
  • 2-[1-(2-Fluoro-3-methylphenyl)cyclobutyl]ethan-1-amine
  • O-({1-[(2,4,5-trifluorophenyl)methyl]cyclopropyl}methyl)hydroxylamine
  • O-[2,2-dimethyl-3-(2,4,5-trifluorophenyl)propyl]hydroxylamine
  • 3-(3-Fluoro-2,6-dimethoxyphenyl)-2,2-dimethylcyclopropan-1-amine
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