Nalmefene

[ Melting Point ]:
188 - 190ºC

[ Molecular Formula ]:
C₂₁H₂₅NO₃

[ Molecular Weight ]:
339.43

[ Exact Mass ]:
339.18300

[ PSA ]:
52.93000

[ LogP ]:
2.45040

[ Storage condition ]:
2-8°C

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Click to get detail synthetic route

Precursor

DownStream

Treatment of alcohol dependence: recent progress and reduction of consumption.

Minerva Med. 105(6) , 447-66, (2014)

Alcohol dependence (AD) is a major public health problem. Currently, three drugs for the treatment of AD have been approved by both the European Medicines Agency (EMA) and the Food and Drug Administra...

Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.

JAMA 311(18) , 1889-900, (2014)

Alcohol use disorders cause substantial morbidity and early mortality yet remain greatly undertreated. Medications are considerably underused.To conduct a systematic review and meta-analysis of the be...

In vivo characterization of the opioid antagonist nalmefene in mice.

Life Sci. 86(15-16) , 624-30, (2010)

The current study assessed the in vivo antagonist properties of nalmefene using procedures previously used to characterize the opioid antagonists naloxone, naltrexone, 6beta-naltrexol and nalbuphine.I...

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