2-Chloro-6-fluorobenzyl chloride

Names

[ Name ]:
2-Chloro-6-fluorobenzyl chloride

[Synonym ]:
Benzene, 1-chloro-2-(chloromethyl)-3-fluoro-
1-Chloro-2-(chloromethyl)-3-fluorobenzene
EINECS 259-487-5
2-Chloro-6-fluorobenzyl chloride
MFCD00000896

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
208.5±25.0 °C at 760 mmHg

[ Melting Point ]:
7 °C

[ Molecular Formula ]:
C₇H₅Cl₂F

[ Molecular Weight ]:
179.019

[ Flash Point ]:
93.3±0.0 °C

[ Exact Mass ]:
177.975235

[ LogP ]:
2.69

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.526

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R34;R51/53

[ Safety Phrases ]:
S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Chloro-6-fluorotoluene
(2-Chloro-6-fluorophenyl)methanol

DownStream

3-[(2-chloro-6-fluorophenyl)methyl]purin-6-amine
Arprinocid
1-chloro-2-ethenyl-3-fluorobenzene
diethyl 2-(2-chloro-6-fluorophenyl)propanedioate
[1,2,5]thiadiazolo[3,4-d]pyrimidin-7-amine
(2-chloro-6-fluoro-benzyl)-[1,2,5]thiadiazolo[3,4-d]pyrimidin-7-yl-amine
2-chloro-6-fluorobenzylamine
9-(2-chloro-6-fluorobenzyl)-6-methylaminopurine
9-(2-chloro-6-fluorobenzyl)-6-dimethylaminopurine

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and antimycobacterial activity of 1,2,4-triazole 3-benzylsulfanyl derivatives.

Il Farmaco 59(4) , 279-88, (2004)

Series of 3-benzylsulfanyl derivatives of 1,2,4-triazole and 4-methyl-1,2,4-triazole were synthesized by alkylation of starting triazole-3-thiol with appropriately substituted benzyl halide. All membe...

Tissue residues of arprinocid in chickens. 1. Depletion of residues in tissues of chickens fed carbon-14-labeled arprinocid.

J. Agric. Food Chem. 30(2) , 248-53, (1982)

New synthesis of a 9-substituted adenine. Hartman GD, et al.

J. Org. Chem. 43(5) , 960-62, (1978)

2-CHLORO-6-FLUOROBENZYL(METHYL)SULFAMOYL CHLORIDE
(2-Chloro-6-fluorobenzyl)hydrazine dihydrochloride
2-Chloro-6-fluorobenzyl bromide
(2-CHLORO-6-FLUOROBENZYL)HYDRAZINEHYDROCHLORIDE
(2-Chloro-6-fluorobenzyl)[2-(2,3-dimethylphenoxy)ethyl]cyanocarbonimidodithioate
(2-Chloro-6-fluorobenzyl)[2-(2-fluorophenoxy)ethyl]cyanocarbonimidodithioate
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(2-methoxypyridin-3-yl)methanone
1-(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)-2-([1,1'-biphenyl]-4-yloxy)ethanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(1H-indol-5-yl)methanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(cyclohex-3-en-1-yl)methanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(thiophen-3-yl)methanone
2-(Cyclopropylmethyl)-3-methoxyphenol
1-(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)-2-(1H-benzo[d][1,2,3]triazol-1-yl)ethanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(2-hydroxyquinolin-4-yl)methanone
(4-(6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-yl)piperazin-1-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone

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