Leupeptin

Suppliers

Names

[ Name ]:
Leupeptin

[Synonym ]:
l-valeramide
acetyl-Leu-Leu-Arg-al
6-O-D-Glucopyranosyl-D-glucopyranose
Ac-Leu-Leu-Arg-aldehyde . sulfate
6-O-B-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE
Gentibiose
Ac-Leu-Leu-Arg-H
N-acetyl-Leu-Leu-argininal
AC-LEU-LEU-ARGINAL 1/2H2SO4 H2O

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₀H₇₈N₁₂O₁₂S

[ Molecular Weight ]:
951.18600

[ Exact Mass ]:
950.55800

[ PSA ]:
415.52000

[ LogP ]:
5.18540

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YV4205100

CHEMICAL NAME :: Valeramide, 2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guan idinobutyl)-4-methyl- (S)-

CAS REGISTRY NUMBER :: 55123-66-5

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H38-N6-O4

MOLECULAR WEIGHT :: 426.64

WISWESSER LINE NOTATION :: MUYZM3YVHMVY1Y1&1&MVYMV1&1Y1&1 S-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 57600 mg/kg/69W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

REFERENCE :: GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 71,913,1980