Davercin

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Names

[ CAS No. ]:
55224-05-0

[ Name ]:
Davercin

[Synonym ]:
Erythromycin Cyclocarbonate
CWE
Erythromycin Cyclocarbonate
Dravercin
Eritromicina A carbonato
Carbonato ciclico de eritromicina a
Cykliczny weglan erytromycyny a
Cykliczny weglan erytromycyny A [polish]
erythromycin A cyclic 11,12-carbonate
Eritromicina A carbonato [spanish]

Chemical & Physical Properties

[ Density]:
1.22 g/cm3

[ Boiling Point ]:
859.8ºC at 760 mmHg

[ Molecular Formula ]:
C38H65NO14

[ Molecular Weight ]:
759.92100

[ Exact Mass ]:
759.44100

[ PSA ]:
188.98000

[ LogP ]:
2.96780

[ Index of Refraction ]:
1.534

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF4670000
CHEMICAL NAME :
Erythromycin, cyclic 11,12-carbonate
CAS REGISTRY NUMBER :
55224-05-0
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C38-H65-N-O14
MOLECULAR WEIGHT :
760.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 31,241,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 31,241,1974

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 3,4-Dihydro-2-(2,4,6-trimethylphenyl)-1(2H)-isoquinolinone
  • 2-Pyrrolidinone, 1-[(1R)-1-(hydroxymethyl)-3-methylbutyl]-
  • 1H-Indene-3-carboxaldehyde, 2-(2,4-dinitrophenyl)hydrazone
  • (2E,6E)-3,7-Dimethyl-10-oxo-2,6-decadien-1-yl 3-pentynoate
  • Ethyl 4-(3-chlorophenyl)-1-methyl-1H-pyrrole-3-carboxylate
  • Benzo[b]thiophene-5-carbonitrile, 6-ethoxy-2-(methylthio)-
  • 1-[(5-Methyl-1H-pyrazol-3-yl)carbonyl]-2,5-piperazinedione
  • (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexanal
  • L-Proline, 1-(N-methyl-D-leucyl)-, 1,1-dimethylethyl ester
  • 5-Chloro-2-(2,4-dinitrophenyl)-1,2-dihydro-1-isoquinolinol
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