Davercin

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Names

[ CAS No. ]:
55224-05-0

[ Name ]:
Davercin

[Synonym ]:
Erythromycin Cyclocarbonate
CWE
Erythromycin Cyclocarbonate
Dravercin
Eritromicina A carbonato
Carbonato ciclico de eritromicina a
Cykliczny weglan erytromycyny a
Cykliczny weglan erytromycyny A [polish]
erythromycin A cyclic 11,12-carbonate
Eritromicina A carbonato [spanish]

Chemical & Physical Properties

[ Density]:
1.22 g/cm3

[ Boiling Point ]:
859.8ºC at 760 mmHg

[ Molecular Formula ]:
C38H65NO14

[ Molecular Weight ]:
759.92100

[ Exact Mass ]:
759.44100

[ PSA ]:
188.98000

[ LogP ]:
2.96780

[ Index of Refraction ]:
1.534

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF4670000
CHEMICAL NAME :
Erythromycin, cyclic 11,12-carbonate
CAS REGISTRY NUMBER :
55224-05-0
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C38-H65-N-O14
MOLECULAR WEIGHT :
760.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 31,241,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 31,241,1974

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • (2R,5R)-1-(11bR)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl-2,5-di-2-naphthalenylpyrrolidine
  • Benzamide,3-fluoro-N-(4-methoxy-2-pyridinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 7-Tributylstannylchromen-2-one
  • (+/-)-Tert-butyl-7-oxo-6-azabicyclo[3.2.0]hept-3-ene-6-carboxylate
  • benzyl N-(1-hydroxyhex-5-en-2-yl)carbamate
  • 2-(1-Benzothiophen-3-yl)propanal
  • 6-methoxy-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-1H-indole-2-carboxamide
  • {2-[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenoxy]-propionylamino}-acetic acid ethyl ester
  • (3-Bromo-5-trifluoromethyl-pyridin-2-yl)-(2-dimethylamino-ethyl)-carbamic acid ethyl ester
  • [4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-carbamic acid ethyl ester
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