4-N-methyl-7H-pyrimido[4,5-b][1,4]thiazine-4,6-diamine
Names
[ CAS No. ]:
55383-59-0
[ Name ]:
4-N-methyl-7H-pyrimido[4,5-b][1,4]thiazine-4,6-diamine
Chemical & Physical Properties
[ Molecular Formula ]:
C7H9N5S
[ Molecular Weight ]:
195.24500
[ Exact Mass ]:
195.05800
[ PSA ]:
98.99000
[ LogP ]:
1.32390
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UW7865000
- CHEMICAL NAME :
- 7H-Pyrimido(4,5-b)(1,4)thiazine, 6-amino-4-methylamino-
- CAS REGISTRY NUMBER :
- 55383-59-0
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H9-N5-S
- MOLECULAR WEIGHT :
- 195.27
- WISWESSER LINE NOTATION :
- T66 BN DN GN JS IHJ EM1 HZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977