Phytosphingosine

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Names

[ CAS No. ]:
554-62-1

[ Name ]:
Phytosphingosine

[Synonym ]:
(2S,3S,4R)-2-Aminooctadecane-1,3,4-triol
Phytosphingosine
(4R,3S,2S)-2-aminooctadecane-1,3,4-triol
PHYTOSPHINGOSINE HYDROCHLORIDE
4-HYDROXYSPHINGANINE
4D-Hydroxysphinganine
1,3,4-Octadecanetriol, 2-amino-, (2S,3S,4R)-
(4R)-4-Hydroxysphinganine
(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
483.7±40.0 °C at 760 mmHg

[ Melting Point ]:
102ºC

[ Molecular Formula ]:
C18H39NO3

[ Molecular Weight ]:
317.507

[ Flash Point ]:
246.4±27.3 °C

[ Exact Mass ]:
317.292999

[ PSA ]:
86.71000

[ LogP ]:
5.18

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.490

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1.0

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-tert-Butyloxycarbonyl-D-ribo-phytosphingosine
  • (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2-phthalimido-3-hydroxy-octadecan-4-yl benzoate

DownStream

  • D-erythro-Sphingosine
  • C18 Phytoceramide (t18:0/18:0)
  • (2s,3r,4e)-2-azido-4-octadecene-1,3-diol
  • (4E,2S,3R)-1,3-Dihydroxy-2-((tert-b

Articles

14-3-3-regulated Ca(2+)-dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis.

Cell Death Differ. 20(2) , 209-17, (2013)

In eukaryotic cells, sphingoid long chain bases (LCBs) such as sphingosine or phytosphingosine (PHS) behave as second messengers involved in various processes including programmed cell death (PCD). In...

Detection of water-soluble disease-associated PrP species in blood and brain of scrapie-infected hamster.

Arch. Virol. 160 , 2219-29, (2015)

The high-speed supernatant (S(HS)) of scrapie-infected hamster brain homogenate contains a soluble infectivity similar to that of the plasma that escapes leukodepletion and can transmit prion infectio...

Morphogenesis checkpoint kinase Swe1 is the executor of lipolysis-dependent cell-cycle progression.

Proc. Natl. Acad. Sci. U. S. A. 112(10) , E1077-85, (2015)

Cell growth and division requires the precise duplication of cellular DNA content but also of membranes and organelles. Knowledge about the cell-cycle-dependent regulation of membrane and storage lipi...


More Articles

Related Compounds

  • phytosphingosine
  • Phytosphingosine slc
  • Phytosphingosine PCA
  • Phytosphingosine HCl
  • C20-Phytosphingosine
  • N-08:0 Phytosphingosine
  • 4-(4-Hydroxyphenyl)-2-methyl-2-(2,2,2-trifluoroacetamido)butanoic acid
  • 4-[2,2,2-trifluoro-N-(4-methoxyphenyl)acetamido]butanoic acid
  • 4-methyl-1-[1-(2,2,2-trifluoroacetyl)piperidin-3-yl]-1H-pyrazole-5-carboxylic acid
  • rac-(3R,4S)-4-(1,5-dimethyl-1H-pyrazol-4-yl)-1-(2,2,2-trifluoroacetyl)pyrrolidine-3-carboxylic acid
  • benzyl N-[4-(2,2-difluoroacetyl)phenyl]carbamate
  • (2R)-2-{[(benzyloxy)carbonyl]amino}-3-(2-hydroxy-1H-imidazol-4-yl)propanoic acid
  • tert-butyl N-[3-(3-nitrophenyl)-1,2-oxazol-5-yl]carbamate
  • 1-[1-(2,2,2-Trifluoroacetyl)piperidin-3-yl]bicyclo[2.1.1]hexane-5-carboxylic acid
  • benzyl N-(1-hydroxybutan-2-yl)-N-(2,2,2-trifluoroethyl)carbamate
  • Ethyl 2-amino-3-(2-fluoro-4-hydroxy-3-methanesulfonylphenyl)propanoate
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