1-nitrosopiperidin-3-ol

Names

[ CAS No. ]:
55556-85-9

[ Name ]:
1-nitrosopiperidin-3-ol

[Synonym ]:
1-Nitroso-3-piperidinol
1-nitroso-piperidin-3-ol
Nitroso-3-piperidinol
3-PIPERIDINOL,N-NITROSO
N-Nitroso-3-piperidinol
N-Nitroso-3-hydroxypiperidine
3-Piperidinol,1-nitroso

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
309.3ºC at 760 mmHg

[ Molecular Formula ]:
C5H10N2O2

[ Molecular Weight ]:
130.14500

[ Flash Point ]:
140.8ºC

[ Exact Mass ]:
130.07400

[ PSA ]:
52.90000

[ LogP ]:
0.06240

[ Index of Refraction ]:
1.588

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN7846000
CHEMICAL NAME :
3-Piperidinol, N-nitroso-
CAS REGISTRY NUMBER :
55556-85-9
BEILSTEIN REFERENCE NO. :
1525252
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H10-N2-O2
MOLECULAR WEIGHT :
130.17
WISWESSER LINE NOTATION :
T6NTJ ANO CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1666 mg/kg/36W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mmol/L
REFERENCE :
TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,129,1984

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Hydroxypiperidine
  • 1-Nitrosopiperidine

DownStream

Related Compounds

  • 1-phenylnonan-3-ol
  • 1-ethoxypentan-3-ol
  • 1-Pentyn-3-ol
  • 1-benzhydrylazetidin-3-Ol
  • 1-butylpiperidin-3-ol
  • 1-Heptyn-3-ol
  • 3-(2,3-Dihydro-1,4-benzodioxin-2-yl)oxolane-2,5-dione
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-3-carbonyl]-4,4-dimethylpyrrolidine-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine