1-nitroso-4-piperidone

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Names

[ CAS No. ]:
55556-91-7

[ Name ]:
1-nitroso-4-piperidone

[Synonym ]:
4-Piperidone,1-nitroso
Nitroso-4-piperidone
1-Nitroso-piperidin-4-on
N-Nitroso-4-piperidinone
N-Nitroso-4-piperidon
Nitroso-4-piperidinone
4-PIPERIDINONE,N-NITROSO
N-Nitroso-4-piperidone
1-nitroso-piperidin-4-one
1-Nitroso-4-piperidone

Chemical & Physical Properties

[ Density]:
1.35g/cm3

[ Boiling Point ]:
313.5ºC at 760 mmHg

[ Molecular Formula ]:
C5H8N2O2

[ Molecular Weight ]:
128.12900

[ Flash Point ]:
143.4ºC

[ Exact Mass ]:
128.05900

[ PSA ]:
49.74000

[ LogP ]:
0.27060

[ Index of Refraction ]:
1.588

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN8990000
CHEMICAL NAME :
4-Piperidinone, N-nitroso-
CAS REGISTRY NUMBER :
55556-91-7
BEILSTEIN REFERENCE NO. :
0113762
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H8-N2-O2
MOLECULAR WEIGHT :
128.15
WISWESSER LINE NOTATION :
T6N DVTJ ANO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1640 mg/kg/36W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1725 mg/kg/30W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
250 ug/plate
REFERENCE :
TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,13,1984

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Piperidone
  • 1-Nitrosopiperidine

DownStream

Related Compounds

  • 3-Methyl-1-nitroso-4-piperidone
  • 1-nitroso-4-(4-nitroso-phenyl)-piperazine
  • 1-Nitroso-4-oxo-2,3,4,5-tetrahydrobenzo-1,5-diazepine
  • 1-nitroso-4-pentoxybenzene
  • 1-nitroso-4-(trideuteriomethyl)piperazine
  • 1-nitroso-4-phenyl-1H-1,4-benzodiazepine-3,5(2H,4H)-dione
  • 2-(4-Chlorophenoxy)-2-methyl-1-[4-(oxolan-3-yl)-1,4-diazepan-1-yl]propan-1-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 10-(tert-Butyldiphenylsilanyloxy)-2-methyldecanoic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-(4-Bromophenyl)-2-[(butoxymethanethioyl)sulfanyl]ethan-1-one
  • (2,4-Difluorophenyl)(4-(((5,6,7,8-tetrahydrocinnolin-3-yl)oxy)methyl)piperidin-1-yl)methanone
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide