1,4-Cyclohexanediol

Names

[ CAS No. ]:
556-48-9

[ Name ]:
1,4-Cyclohexanediol

[Synonym ]:
Cyclohexan-1,4-diol
1,4-Cyclohexanediol
MFCD00001448
Quinitol
EINECS 209-126-2
Cyclohexane-1,4-diol

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
252.4±0.0 °C at 760 mmHg

[ Melting Point ]:
98-100ºC

[ Molecular Formula ]:
C₆H₁₂O₂

[ Molecular Weight ]:
116.158

[ Flash Point ]:
65.6±0.0 °C

[ Exact Mass ]:
116.083733

[ PSA ]:
40.46000

[ LogP ]:
-0.09

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.527

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
22-37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 1325

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
29061900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Hydroquinone
4-(4-methylbenzoyloxy)cyclohexyl 4-(trifluoromethyl)benzoate
cyclohexane
1,4-Cyclohexanedione
Silane, [1,4-cyclohexanediylbis(oxy)]bis[trimethyl-
Cyclohexanone
cis-cyclohex-2-ene-1,4-diol
4-Hydroxycyclohexanone
4-(4-Fluorophenoxy)phenol

DownStream

tert-butyl-cyclohex-3-en-1-yloxy-dimethylsilane
acetic acid,cyclohex-3-en-1-ol
4-Oxocyclohexyl acetate
4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanone
delta-Valerolactone
Dimethyl adipate
6-hydroxyhexanoic acid methyl ester
Methyl glutarate
5-Hydroxypentanoic acid methyl ester
1,2-Cyclohexanediol

Customs

[ HS Code ]: 29061900

Articles

Core-shell polymer nanoparticles for prevention of GSH drug detoxification and cisplatin delivery to breast cancer cells.

Nanoscale 7 , 17964-79, (2015)

Platinum drug delivery against the detoxification of cytoplasmic thiols is urgently required for achieving efficacy in breast cancer treatment that is over expressed by glutathione (GSH, thiol-oligope...

Biological monitoring of occupational exposure to cyclohexane by urinary 1,2- and 1,4-cyclohexanediol determination.

Int. Arch. Occup. Environ. Health 72(2) , 115-20, (1999)

This article reports the results obtained with the biological and environmental monitoring of occupational exposure to cyclohexane using 1,2-cyclohexanediol (1,2-DIOL) and 1,4-DIOL in urine. The kinet...

Oxidation of cyclohexanediol derivatives with 12-tungstophosphoric acid-hydrogen peroxide system.

J. Oleo Sci. 58(6) , 323-8, (2009)

Oxidation of cyclohexanediol derivatives with 12-tungstophospholic acid-hydrogen peroxide system was investigated focusing on a reaction mechanism in the preparation of dicarboxylic acids from olefin ...