H-Gly-Gly-OH

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Names

[ CAS No. ]:
556-50-3

[ Name ]:
H-Gly-Gly-OH

[Synonym ]:
2-(2-AMINOTHIAZOL-4-YL) GLYOXYLIC ACID
(2-amino-thiazol-4-yl)-oxo-acetic acid
ATGA:2-(2-AMINOTHIAZOL-4-YL) GLYOXYLIC ACID
Glycyl-glycine
Glycine, glycyl-
2-(2-Aminothiazol-4-yl)-2-oxoacetic acid
N-Glycylglycine
Glycylglycine
H-Gly-Gly-OH
glycine anhydride
2-(2-ammonioacetamido)acetate
(2-aminothiazol-4-yl)glyoxylic acid
ATGA
Diglycocoll
H2N-Gly-Gly-OH
diglycine
MFCD00008130
(2-amino-4-thiazolyl)glyoxylic acid
EINECS 209-127-8
2-(2-aminothiazol-4-yl)glyoxylic Acid (ATGA)
2-oxo-2-(2-aminothiazol-4-yl)acetic acid
glycine dipeptide
Gly-gly

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
453.2±30.0 °C at 760 mmHg

[ Melting Point ]:
220-240 °C (dec.)

[ Molecular Formula ]:
C4H8N2O3

[ Molecular Weight ]:
132.118

[ Flash Point ]:
227.9±24.6 °C

[ Exact Mass ]:
132.053497

[ PSA ]:
92.42000

[ LogP ]:
-1.85

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.505

[ Storage condition ]:
-15°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
SOLUBLE IN HOT WATER

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S24/25-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

  • H-Gly-Gly-OEt.HCl
  • H-Gly-Gly-NH2
  • N-[(Benzyloxy)carbonyl]glycylglycine
  • 2-[[2-(tritylamino)acetyl]amino]acetic acid
  • Glycine
  • N-(tert-Butoxycarbonyl)glycylglycin
  • Glycine,N-(2-chloroacetyl)glycyl-
  • N-(N-benzyloxycarbonyl-glycyl)-glycine-(4-nitro-benzyl ester)
  • N-{N-[(2-nitro-phenoxy)-acetyl]-glycyl}-glycine

DownStream

  • Fmoc-Gly-Gly-OH
  • N-(tert-Butoxycarbonyl)glycylglycin
  • Acetamide
  • Acetamide,N,N'-methylenebis-
  • Acetamidomethanol
  • Ac-Gly-OH
  • H-Glu(Gly-Gly-OH)-OH
  • 4-Nitroaniline
  • (2Z)-2-[1,11-diamino-10-(carboxymethylideneamino)-2,10-dihydroxy-3,9-d ioxo-undecan-2-yl]iminoacetic acid
  • CAY10679

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Abiogenic Syntheses of Lipoamino Acids and Lipopeptides and their Prebiotic Significance.

Orig. Life Evol. Biosph. 45 , 427-37, (2015)

Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino ...

Recurrence of carbamoyl phosphate synthetase 1 (CPS1) deficiency in Turkish patients: characterization of a founder mutation by use of recombinant CPS1 from insect cells expression.

Mol. Genet. Metab. 113(4) , 267-73, (2014)

Carbamoyl phosphate synthetase 1 (CPS1) deficiency due to CPS1 mutations is a rare autosomal-recessive urea cycle disorder causing hyperammonemia that can lead to death or severe neurological impairme...

Inhibition of calcium-calmodulin complex formation by vasorelaxant basic dipeptides demonstrated by in vitro and in silico analyses.

Biochim. Biophys. Acta 1840(10) , 3073-8, (2014)

Tryptophan-histidine (Trp-His) was found to suppress the activity of the Ca²⁺/calmodulin (CaM)-dependent protein kinases II (CaMKII), which requires the Ca²⁺-CaM complex for an initial activation. In ...


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Related Compounds

  • N-{2-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]ethyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)benzo[d]thiazole-2-carboxamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)-2-((4-fluorophenyl)thio)acetamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)-5-methylisoxazole-3-carboxamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)-3-(dimethylamino)benzamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)benzo[c][1,2,5]thiadiazole-5-carboxamide
  • 3-Cyclopropoxy-N,N-dimethyl-5-(trifluoromethyl)pyridin-4-amine
  • N-(2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide
  • 4-Cyclopropoxy-3-(dimethylamino)-N-methylbenzamide
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