4-[(2,4-Diaminopyrimidine-5-yl)methyl]-2,6-dimethoxy-α,α-dimethylbenzenemethanol

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Names

[ CAS No. ]:
55687-91-7

[ Name ]:
4-[(2,4-Diaminopyrimidine-5-yl)methyl]-2,6-dimethoxy-α,α-dimethylbenzenemethanol

[Synonym ]:
DHFR inhibitor

Chemical & Physical Properties

[ Density]:
1.245g/cm3

[ Boiling Point ]:
610ºC at 760 mmHg

[ Molecular Formula ]:
C16H22N4O3

[ Molecular Weight ]:
318.37100

[ Flash Point ]:
322.7ºC

[ Exact Mass ]:
318.16900

[ PSA ]:
117.97000

[ LogP ]:
1.33660

[ Index of Refraction ]:
1.612

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Guanidine hydrochloride
  • 2-(4-(2-hydroxypropan-2-yl)-3,5-dimethoxybenzyl)-3-(phenylamino)acrylonitrile
  • 1,1,1-trichloro-2-isocyanatoethane
  • methyl 4-formyl-2,6-dimethoxybenzoate
  • methyl 2,6-dimethoxy-4-(α,α-diethoxymethyl)benzoate
  • 4-(1-hydroxy-1-methylethyl)-3,5-dimethoxybenzaldehyde
  • 2-(N-phthalimidoethyl)-1,2,3-benzotriazole

DownStream