(Z)-4-Amino-4-oxobut-2-enoic acid

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Names

[ CAS No. ]:
557-24-4

[ Name ]:
(Z)-4-Amino-4-oxobut-2-enoic acid

[Synonym ]:
Maleamic acid
Aminomaleic acid
Maleinamidsaeure
Maleamidic acid
3c-carbamoyl-acrylic acid
EINECS 209-163-4
Maleic monoamide
MELEAMICACID
maleinamic acid
AURORA KA-4159
maleic acid monoamide
N-[p-(Acetylmercuric)phenyl]maleamate
Maleamate
MFCD00082354
maleamic

Chemical & Physical Properties

[ Density]:
1.376g/cm3

[ Boiling Point ]:
408.6ºC at 760mmHg

[ Melting Point ]:
158-161 °C(lit.)

[ Molecular Formula ]:
C4H5NO3

[ Molecular Weight ]:
115.08700

[ Flash Point ]:
200.9ºC

[ Exact Mass ]:
115.02700

[ PSA ]:
80.39000

[ Index of Refraction ]:
1.528

[ Stability ]:
Stable, but light sensitive. Incompatible with strong oxidizing agents.

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

  • Maleic anhydride
  • beta-Alanine
  • 5-azidofuran-2-carbaldehyde
  • 4-AMINOBENZOPHENONE
  • H-D-Val-OH
  • 4-amino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine
  • 2-[2-(2-aminophenyl)sulfanylethylsulfanyl]aniline
  • methyl 4-aminobenzoate,hydrochloride
  • Maleimide
  • L-asparagine

DownStream

  • 3-oxauracil
  • Ethyl cis-beta-cyanoacrylate
  • fumaric acid
  • Maleimide
  • 3-carbamoyl-2-methylamino-propanoic acid
  • p Tolylmaleimide
  • 3-carbamoyl-2-ethylamino-propanoic acid
  • 2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetamide
  • 3-(carboxyamino)prop-2-enoic acid
  • 4-amino-2-(benzylamino)-4-oxobutanoic acid

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Hapten synthesis and development of a competitive indirect enzyme-linked immunosorbent assay for acrylamide in food samples.

J. Agric. Food Chem. 62(29) , 7078-84, (2014)

The high level of acrylamide in widely consumed processed foods poses a potentially significant risk to human health, which has led to an increasing demand for rapid, simple, and selective analytical ...

N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids.

Bioorg. Med. Chem. 16 , 560-8, (2008)

N-Phenyl and N-phenylalkyl maleimides (alkyl chain=(CH(2))n; n=0-4) and their respective open derivatives (maleamic acids) were evaluated against Candida spp. with the microbroth dilution method follo...

Selective adsorption of D- and L-phenylalanine on molecularly-imprinted polymerized organogels formed using polymerizable gelator N-octadecyl maleamic acid.

J. Sep. Sci. 31(21) , 3782-7, (2008)

The polymerizable gelator N-octadecyl maleamic acid (ODMA) can self-assemble in selected polymerizable organic solvents, such as 2-hydroxyethyl methacrylate (HEMA) and methylacrylic acid (MAA) to form...


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Related Compounds

  • (Z)-4-amino-4-oxobut-2-enoic acid
  • (Z)-4-amino-4-oxobut-2-enoic acid,azane,methoxyethene
  • (Z)-4-((2-ethoxyphenyl)amino)-4-oxobut-2-enoic acid
  • (Z)-4-((5-methylisoxazol-3-yl)amino)-4-oxobut-2-enoic acid
  • N-(2,6-DIETHYLPHENYL)MALEAMIC ACID
  • N-(3,5-dichlorophenyl)maleamic acid
  • maleylphenylalanine methyl ester