N-Succinimidyl 6-maleimidohexanoate

Suppliers

Names

[ Name ]:
N-Succinimidyl 6-maleimidohexanoate

[Synonym ]:
1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
MFCD00043043
1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-
(2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
N-succinimidyl-6-maleimidocaproate
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
MCOSU
EMCS

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
480.6±47.0 °C at 760 mmHg

[ Melting Point ]:
70-73 °C(lit.)

[ Molecular Formula ]:
C₁₄H₁₆N₂O₆

[ Molecular Weight ]:
308.287

[ Flash Point ]:
244.5±29.3 °C

[ Exact Mass ]:
308.100830

[ PSA ]:
101.06000

[ LogP ]:
-0.81

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.577

[ Storage condition ]:
−20°C

[ Water Solubility ]:
chloroform: 100mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H351

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P337 + P313

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N,N'-Disuccinimidyl carbonate
6-Maleimidocapronic acid
Maleic anhydride
N-Hydroxysuccinimide
6-Aminocaproic acid
6-[[(2Z)-3-carboxy-1-oxo-2-propenyl]amino]hexanoic acid

DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor.

J. Bacteriol. 197 , 3110-20, (2015)

A number of investigations of Escherichia coli have suggested that the DNA-binding protein H-NS, in addition to its well-known functions in chromosome organization and gene regulation, interacts direc...

Successful acquisition of a neutralizing monoclonal antibody against a novel neutrophil-activating peptide, mitocryptide-1.

Biochem. Biophys. Res. Commun. 463 , 54-9, (2015)

Mitocryptide-1 (MCT-1) is a novel neutrophil-activating peptide derived from mitochondrial cytochrome c oxidase subunit VIII, and its physiological role and involvement in various diseases have not ye...

Moderate PEGylation of the carrier protein improves the polysaccharide-specific immunogenicity of meningococcal group A polysaccharide conjugate vaccine.

Vaccine 33 , 3208-14, (2015)

Neisseria meningitidis can cause severe and fulminant diseases such as meningitis. Meningococcal capsular polysaccharide (PS) is a key virulence determinant that is not able to induce immunological me...

N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE
N-Succinimidyl 6-[[4-(N-Maleimidomethyl)cyclohexyl]carboxamido]hexanoate
SMPH Crosslinker
Sulfo-NHS-LC-Biotin sodium
Sulfo-SPDP-C6-NHS sodium
N-succinimidyl-4-[(6-hydroxyhexyloxy)diphenylmethyl]benzoate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
2-chloro-5-(4,4-dimethyl-1,1-dioxido-3-oxoisothiazolidin-2-yl)-N-(2-fluorophenyl)benzamide
8-{[1,1'-Biphenyl]-4-carbonyl}-4-(4-methylbenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane
N-(4-acetamidophenyl)-2-((6-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)acetamide
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
(2R)-2-Amino-4-(diethylamino)butanoic acid