Dimefadane

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Names

[ CAS No. ]:
5581-40-8

[ Name ]:
Dimefadane

[Synonym ]:
Dimefadano [INN-Spanish]
N,N-Dimethyl-3-phenyl-1-indanamine
SKF 1340
1H-Inden-1-amine,2,3-dihydro-N,N-dimethyl-3-phenyl
Dimefadanum [INN-Latin]
dimethyl-(3-phenyl-indan-1-yl)-amine
clothiapine
Dimethyl fandane
DIMEFADANE
Dimefadane [USAN:INN]
F 1340
1-Indanamine,N,N-dimethyl-3-phenyl
Dimethyl-(3-phenyl-indan-1-yl)-amin

Chemical & Physical Properties

[ Density]:
1.07g/cm3

[ Boiling Point ]:
349.7ºC at 760 mmHg

[ Molecular Formula ]:
C17H19N

[ Molecular Weight ]:
237.33900

[ Flash Point ]:
149.5ºC

[ Exact Mass ]:
237.15200

[ PSA ]:
3.24000

[ LogP ]:
3.82490

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK4025000
CHEMICAL NAME :
1-Indanamine, N,N-dimethyl-3-phenyl-
CAS REGISTRY NUMBER :
5581-40-8
BEILSTEIN REFERENCE NO. :
3322336
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H19-N
MOLECULAR WEIGHT :
237.37
WISWESSER LINE NOTATION :
L56T&J BN1&1 DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
176 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Phenyl-indan-1-ol
  • 3-Phenyl-1-indanone
  • Formaldehyde
  • 3-phenyl-indan-1-ylamine, hydrochloride
  • Dimethylamine
  • 1-chloro-3-phenyl-indan

DownStream


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Tert-butyl 2-(2-fluoro-5-nitrophenyl)piperazine-1-carboxylate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3-(5-Methylfuran-2-yl)oxolane-2,5-dione
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine