L-Lysine

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Names

[ CAS No. ]:
56-87-1

[ Name ]:
L-Lysine

[Synonym ]:
L-lys
Lisina [Spanish]
6-Amino-L-norleucine
(+)-S-Lysine
Lys
L-Lysine (9CI)
(l)-lysine
(S)-(+)-Lysine
Aminutrin
Lysine acid
(S)-a,e-Diaminocaproic Acid
Lysinum [Latin]
(S)-lysine
Lysine
2,6-Diaminohexanoic acid, (S)-
FEMA 3847
(S)-2,6-diamino-Hexanoic acid
L-Lysine
Lysine, L-
MFCD00064433
EINECS 200-294-2
H-Lys-OH
L-lysine zwitterion

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
311.5±32.0 °C at 760 mmHg

[ Melting Point ]:
215 °C (dec.)(lit.)

[ Molecular Formula ]:
C6H14N2O2

[ Molecular Weight ]:
146.188

[ Flash Point ]:
142.2±25.1 °C

[ Exact Mass ]:
146.105530

[ PSA ]:
89.34000

[ LogP ]:
-1.04

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.503

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, colorless

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5540000
CHEMICAL NAME :
Lysine, L-
CAS REGISTRY NUMBER :
56-87-1
BEILSTEIN REFERENCE NO. :
1722531
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C6-H14-N2-O2
MOLECULAR WEIGHT :
146.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
138 gm/kg
SEX/DURATION :
female 5-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
72450 mg/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
90450 mg/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
81 gm/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
44 gm/kg
SEX/DURATION :
female 5-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
OL5540000

[ HS Code ]:
2922411000

Synthetic Route

Precursor & DownStream

Precursor

  • DL-Lysine
  • Z-Lys(Z)-OH
  • Z-Lys-OH
  • Fmoc-Lys-OH

DownStream

  • Fmoc-Lys(Trt)-OH
  • Biocytin
  • 2,3-Dimethylpyrazine
  • 2-Ethyl-3,5-dimethylpyrazine
  • 5-Isobutyl-2,3-dimethylpyrazine
  • 2-Ethyl-3,5-dimethylpyrazine
  • 2-acetyl-6-methyl pyrazine
  • 2-acetyl-5-methyl pyrazine
  • 3,5-dimethyl-2-(2-methylpropyl)pyrazine
  • 2-Ethyl-5-methylpyrazine

Customs

[ HS Code ]: 2922411000

[ Summary ]:
HS: 2922411000. 2,6-diaminohexanoic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:5.0%. general tariff:20.0%

Articles

Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine.

FEBS J. 281(24) , 5498-512, (2014)

D-Phosphoglycerate dehydrogenase (PGDH) catalyzes the first committed step of the phosphorylated serine biosynthesis pathway. Here, we report for the first time, the crystal structures of Type IIIK PG...

ALD1 Regulates Basal Immune Components and Early Inducible Defense Responses in Arabidopsis.

Mol. Plant Microbe Interact. 28(4) , 455-66, (2015)

Robust immunity requires basal defense machinery to mediate timely responses and feedback cycles to amplify defenses against potentially spreading infections. AGD2-LIKE DEFENSE RESPONSE PROTEIN 1 (ALD...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotop...


More Articles


Related Compounds

  • L-Lysine-d4
  • L-LYSINE AC
  • L-lysine*TFA
  • L-Lysine HCl
  • L-Lysine-d4-1
  • L-LYSINE 2HCL
  • (2R,3S,4R)-2-[(benzoyloxy)methyl]-4-cyano-4-methyl-5-oxooxolan-3-ylbenzoate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 6-(Aminomethyl)-4-methylpyridin-2-OL
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • methyl 4-(N-(2-(2-chlorophenyl)-2-methoxyethyl)sulfamoyl)benzoate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde