Demecarium bromide
Suppliers
Names
[ CAS No. ]:
56-94-0
[ Name ]:
Demecarium bromide
[Synonym ]:
Tosmilen
3,3'-{1,10-Decanediylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide
Visumiotic
Demekastigmine bromide
3,3'-{Decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide
Tonilen
trimethyl-[3-[methyl-[10-[methyl-[3-(trimethylazaniumyl)phenoxy]carbonylamino]decyl]carbamoyl]oxyphenyl]azanium,dibromide
3,3'-[1,10-Decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethylbenzenaminium]dibromide
Benzenaminium, 3,3'-[1,10-decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethyl-, bromide (1:2)
Humorsol
Tosmicil
decamethylenebis[m-dimethylaminophenyl n-methylcarbamate] dimethobromide
Decamethylenebis[N-methylcarbamic Acid m-Dimethylaminophenyl Ester] Bromidethylate
Tosmilene
EINECS 200-301-9
Demecarium bromide
N,N'-Bis[3-trimethylammoniumphenoxycarbonyl]-N,N'-dimethyldecamethylenediamine Dibromide
Frumtosnil
Visumatic
Chemical & Physical Properties
[ Melting Point ]:
164 - 170ºC
[ Molecular Formula ]:
C32H52Br2N4O4
[ Molecular Weight ]:
716.588
[ Exact Mass ]:
714.235535
[ PSA ]:
59.08000
[ LogP ]:
0.77020
[ Storage condition ]:
2-8℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BR3130000
- CHEMICAL NAME :
- Ammonium, (m-hydroxyphenyl)trimethyl-, bromide, decamethylenebis(methylcarbamate)
- CAS REGISTRY NUMBER :
- 56-94-0
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C32-H52-N4-O4.2Br
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6490 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,168,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 29 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,307,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 24500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,168,1967 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3186 No. of Facilities: 9 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 3239 (estimated) No. of Female Employees: 1168 (estimated)
Safety Information
[ Safety Phrases ]:
S22-S26-S36/37-S36/37/39
[ RIDADR ]:
3077
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
9