(Pyr5)-Substance P (5-11)

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Names

[ Name ]:
(Pyr5)-Substance P (5-11)

[Synonym ]:
5-Oxo-L-prolyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide
[pGlu5]-Substance P Fragment 5-11
pGlu-Gln-Phe-Phe-Gly-Leu-Met-NH2
L-Methioninamide, 5-oxo-L-prolyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1374.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₁H₅₇N₉O₉S

[ Molecular Weight ]:
852.011

[ Flash Point ]:
785.3±34.3 °C

[ Exact Mass ]:
851.400024

[ PSA ]:
315.18000

[ LogP ]:
0.64

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.581

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Biological activity of C-terminal partial sequences of substance P.

J. Med. Chem. 19 , 854, (1976)

Substance P (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) and the C-terminal partial sequences down to the tripeptide were synthesized by a solid-phase method. These peptides were assayed for vaso...

(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11)
[Glp5,Sar9] Substance P (5-11)
Galanin (1-13)-Substance P (5-11) amide
(D-GLU5,D-TRP7,9,10)-SUBSTANCE P (5-11)
Substance P (5-11), asparaginyl(5,6)-methylphenylalanine(8)-
substance P (5-11), N-alpha-(desamino-3-iodotyrosyl)-8-N-me-Phe-5,6-Asp-
2,5-difluoro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)benzenesulfonamide
2-chloro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)benzenesulfonamide
4-fluoro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)benzenesulfonamide
3-chloro-4-fluoro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)benzenesulfonamide
N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)-4-methoxybenzenesulfonamide
N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide
3-fluoro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)-4-methoxybenzenesulfonamide
N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
5-ethyl-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)thiophene-2-sulfonamide
5-chloro-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)ethyl)thiophene-2-sulfonamide

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