Chlorphenoxamine Hydrochloride

Suppliers

Names

[ CAS No. ]:
562-09-4

[ Name ]:
Chlorphenoxamine Hydrochloride

[Synonym ]:
Systral
EINECS 209-227-1
Chlorphenoxamine HCl
{2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine,hydrochloride
chlophenoxamine hydrochloride
Phenoxene
chlorophenoxamine hydrochloride
Contristamine,hydrochloride
2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]-N,N-dimethylethanamine hydrochloride
Chlorphenoxamine hydrochloride
Substanz NR. 1766 [German]
{2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin,Hydrochlorid
Phenoxene hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
383.7ºC at 760 mmHg

[ Molecular Formula ]:
C18H23Cl2NO

[ Molecular Weight ]:
340.28700

[ Flash Point ]:
185.9ºC

[ Exact Mass ]:
339.11600

[ PSA ]:
12.47000

[ LogP ]:
4.98370

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR2975000
CHEMICAL NAME :
Ethylamine, 2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N -dimethyl-, hydrochloride
CAS REGISTRY NUMBER :
562-09-4
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C18-H22-Cl-N-O.Cl-H
MOLECULAR WEIGHT :
340.32
WISWESSER LINE NOTATION :
GR DX1&R&O2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,31,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
345 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,262,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
161 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,83,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
159 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,262,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,262,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
30800 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,638,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 3-[(5-Fluoro-2-hydroxyphenyl)methyl]azetidin-3-ol
  • 3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)but-2-ynamido]oxolane-2-carboxylic acid
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-({3-oxabicyclo[3.1.0]hexan-1-yl}carbamoyl)butanoic acid
  • 3-{[(Butan-2-yl)amino]methyl}-2,4-dimethylaniline
  • 2-(5-Bromo-2-fluorophenyl)cyclobutan-1-ol
  • tert-butyl N-{2-hydroxy-5-[(3-hydroxypyrrolidin-3-yl)methyl]-3-methoxyphenyl}carbamate
  • [3-(4-Chloro-2-methoxyphenyl)-2,2-dimethylcyclopropyl]methanamine
  • 4-(Diethylamino)-2-hydroxybenzene-1-sulfonamide
  • 2-(2-Chloro-5,6,7,8-tetrahydroquinolin-3-yl)-3,3,3-trifluoropropan-1-amine
  • 4-Methyl-1-[(thiophen-3-yl)methyl]cyclohex-2-en-1-ol
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.