4,4'-Methylenedimorpholine
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Names
[ CAS No. ]:
5625-90-1
[ Name ]:
4,4'-Methylenedimorpholine
[Synonym ]:
4-(morpholin-4-ylmethyl)morpholine
Morpholine, 4,4'-methylenebis-
4,4'-Methylenedimorpholine
EINECS 227-062-3
4,4'-methanediyldimorpholine
MFCD00593814
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
265.1±35.0 °C at 760 mmHg
[ Molecular Formula ]:
C9H18N2O2
[ Molecular Weight ]:
186.251
[ Flash Point ]:
77.6±23.2 °C
[ Exact Mass ]:
186.136826
[ PSA ]:
24.94000
[ LogP ]:
-0.06
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.497
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QE6125000
- CHEMICAL NAME :
- Morpholine, 4,4'-methylenedi-
- CAS REGISTRY NUMBER :
- 5625-90-1
- BEILSTEIN REFERENCE NO. :
- 0111886
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H18-N2-O2
- MOLECULAR WEIGHT :
- 186.29
- WISWESSER LINE NOTATION :
- T6N DOTJ A1- AT6N DOTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 71,105,1968 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 6,576,1968
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2000 mg/kg/40W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Peripheral Nerve and Sensation - peripheral nerve tumors Tumorigenic - tumors at site of application
- REFERENCE :
- ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 71,105,1968
Safety Information
[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
26-36/37/39