Isobutyramide

Suppliers

Names

[ CAS No. ]:
563-83-7

[ Name ]:
Isobutyramide

[Synonym ]:
2-methylpropaneamide
EINECS 209-265-9
Propanamide, 2-methyl-
isopropylformamide
IBA
iso-Butyleneamine
isobutyrimidicacid
Isobutyramide
isobutyric amide
MFCD00008019
Isobuytramide
2-Methylpropanamide
anhydrous dimethyl-acetamide
Methyl propionic acid amide
VX 366
2-methylpropionamide

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
221.4±8.0 °C at 760 mmHg

[ Melting Point ]:
127-131 °C(lit.)

[ Molecular Formula ]:
C₄H₉NO

[ Molecular Weight ]:
87.120

[ Flash Point ]:
87.7±18.4 °C

[ Exact Mass ]:
87.068413

[ PSA ]:
43.09000

[ LogP ]:
-0.36

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.418

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX1475000

CHEMICAL NAME :: Propanamide, 2-methyl-

CAS REGISTRY NUMBER :: 563-83-7

BEILSTEIN REFERENCE NO. :: 1737615

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H9-N-O

MOLECULAR WEIGHT :: 87.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5439939

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TX1475000

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Isobutyric acid
Isobutyronitrile
Isobutyraldehyde
2-methyl-N-phenyl-propanehydrazide
isopropylamine
Isobutylene
Oxalyl chloride
tert-Butylamine
Methacrylonitrile
Methacrylamide

DownStream

2-METHYLPROPIONIMIDIC ACID ETHYL ESTER
1,1,3,3-Propanetetracarboxamide
isopropylamine
Isobutyric acid hydrazide
Ceftazidime
Methyl isobutyrate
5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride
Isobutyronitrile
Water
Ammonia

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9.

PLoS ONE 11 , e0145212, (2016)

Poor outcome in response to hepatitis C virus, including higher viral load, hepatocellular carcinoma and cirrhosis, is more associated with men and postmenopausal women than with premenopausal women a...

Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.

Blood 101(5) , 2001-7, (2003)

Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia. In this study, we have investigated the HbF-inducing activity and mole...

Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones.

J. Mol. Endocrinol. 25(1) , 129-39, (2000)

To determine if ketoacidosis contributes to reduced apolipoprotein A1 (apoA1) expression in insulin-deficient diabetic rats, we examined the regulation of apoA1 gene expression in response to changes ...