Tibolone(Liviella)(Livial)

Suppliers

Names

[ Name ]:
Tibolone(Liviella)(Livial)

[Synonym ]:
EINECS 227-069-1
17-Hydroxy-7α-methyl-19-nor-17α-pregn-5(10)-en-20-yn-3-one
Tibolone
7a-Methyl-5,10-norethindrone
7a-Methyl-17a-ethynyl-17b-hydroxy-19-norandrost-5(10)-en-3-one
LIVIELLA
19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-7-methyl-, (7α,17α)-
Org OD 14
(7α,17α)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
7a-Methyl-D5,10-norethindrone
(7R,8R,9S,13S,14S,17R)-17-Ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Estr-5(10)-en-3-one, 17-ethynyl-17-hydroxy-7-methyl-, (7α,17β)-
Livial
7a-Methyl-17a-ethynyl-17b-hydroxyestr-5(10)-en-3-one
MFCD00864178
(7a,17a)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
447.4±45.0 °C at 760 mmHg

[ Melting Point ]:
169 °C

[ Molecular Formula ]:
C₂₁H₂₈O₂

[ Molecular Weight ]:
312.446

[ Flash Point ]:
190.6±21.3 °C

[ Exact Mass ]:
312.208923

[ PSA ]:
37.30000

[ LogP ]:
4.03

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.570

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
N

[ Risk Phrases ]:
R51/53

[ Safety Phrases ]:
S22-S24/25-S61

[ RIDADR ]:
UN 3077 9/PG 3

[ RTECS ]:
RC8964020

Precursor & DownStream

Precursor

2-Dehydro-3-methoxy Tibolone
Tibolone 3-Ethylene Ketal
Tibolone 3-Dimethyl Ketal
Estra-1,3,5(10)-trien-17-one,3-methoxy-7-methyl-, (7a)- (9CI)
3-Methoxy-7α-methyl-estra-2,5(10)-dien-17β-ol
3-Methoxy-7α-methyl-estra-2,5(10)-dien-17-one
(7α,17β)-3-Methoxy-7-methyl-estra-1,3,5(10)-trien-17-ol
7α-methylestr-5(10)-ene-3,17-dione
7α-Methyl-3,3-dimethoxy-5(10)-estrene-17-one
7α-methyl-3,17-dioxoandrost-4-en-19-al

DownStream

Articles

Tibolone prevents oxidation and ameliorates cholinergic deficit induced by ozone exposure in the male rat hippocampus.

Neurochem. Res. 39(9) , 1776-86, (2014)

Oxidative stress is related to the development of central nervous system diseases involving memory processes. Cholinergic system and memory processes are disrupted by ozone exposure. In rats, ozone in...

Effects of tibolone or continuous combined oestradiol/norethisterone acetate on glucose and insulin metabolism.

Clin. Endocrinol. (Oxf.) 78(2) , 297-302, (2013)

To determine the effects of tibolone or oestradiol (E(2) )/norethisterone acetate (NETA) hormone replacement therapy on glucose and insulin metabolism in postmenopausal women.Single-centre double-blin...

Effects of a continuous-combined regimen of low-dose hormone therapy (oestradiol and norethindrone acetate) and tibolone on the quality of life in symptomatic postmenopausal women: a double-blind, randomised study.

Maturitas 74(2) , 172-8, (2013)

This study compared the effects of a continuous-combined regimen of low-dose hormone therapy (LD-HT) versus tibolone and supplemental calcium/vitamin D3 (control) on quality of life (QoL) in symptomat...

Tibolone 3-Ethylene Ketal
Tibolone 3-Dimethyl Ketal
tibolone-17β-sulfate
(6R,7R)-3-(acetyloxymethyl)-7-[(2-bromoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
[6R-(6alpha,7beta)]-3-(acetoxymethyl)-7-(hydroxyphenylacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7β-Tibolone